OFD1 and KIAA1377

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		OFD1	KIAA1377
Gene Name		oral-facial-digital syndrome 1	KIAA1377
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Centrosome Centriole Cytosol Cilium Microtubule Cytoskeleton Membrane Centriolar Satellite Ciliary Basal Body	Cytoplasm Centrosome Midbody Ciliary Base
	Molecular Function	Protein Binding Alpha-tubulin Binding Gamma-tubulin Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Centriole Replication Embryonic Body Morphogenesis Axoneme Assembly Cilium Morphogenesis Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Mitotic Spindle Assembly Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation	Mitotic Spindle Organization Cytoplasmic Microtubule Organization Cilium Assembly
Pathways		Organelle biogenesis and maintenance Hedgehog 'off' state Assembly of the primary cilium G2/M Transition Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes Signaling by Hedgehog Centrosome maturation Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CCSER2 EIF6 GPRASP1 KIAA1377 LUC7L2 NME7 PLK1 RUVBL1	86 interactors: AIMP2 AKTIP ARIH2 ATP6V1F ATRX BMI1 BRD1 C11orf58 CDKN2B CRCT1 CSTF2 DGCR6 DISC1 DLEU1 DNM1 DUSP12 DUSP23 EIF2S2 EIF6 EPN1 FAM118B FAM134A FEZ1 FGFR3 FXR1 GEMIN7 GET4 GIT1 GOLGB1 GPRASP2 GSTO1 HMOX2 HTT ING5 KAT5 KAT7 KIF15 KLHL20 LAMTOR5 LPL LRRC1 LUC7L2 MAD2L1BP MAPK9 MRPS6 NAP1L5 NAT9 NPM3 NSF NUDT21 ODF2L OFD1 PBK PDCD5 PFDN1 PIK3R3 PMF1 POLD1 POLR2M PPP1CA PPP1CC PRKRA PTPRS RAB27A RAN RBM23 RGS2 RIF1 ROGDI RPA2 RUVBL1 SAT1 SNRPG SPDL1 STAU2 TFG TNFRSF14 TNFSF11 TOMM20 TTR TXNDC9 VIM YAE1D1 YWHAZ ZBED8 ZNF24
Entrez ID		8481	57562
HPRD ID		02162	17212
Ensembl ID		ENSG00000046651	ENSG00000110318
Uniprot IDs		A6NF31 A8K2T9 E9KL37 O75665	Q9P2H0
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule-based Process Microtubule Bundle Formation Organelle Organization Microtubule Cytoskeleton Organization Activation Of APC-Cdc20 Complex Activity G-protein Coupled Receptor Catabolic Process Cellular Macromolecular Complex Assembly Mitotic Cell Cycle Process Polar Body Extrusion After Meiotic Divisions Ribonucleoprotein Complex Assembly Mitotic Cell Cycle Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Cilium Organization Mature Ribosome Assembly Cellular Component Assembly Activation Of Anaphase-promoting Complex Activity Meiotic Cytokinesis Positive Regulation Of Mitotic Metaphase/anaphase Transition Metaphase/anaphase Transition Of Mitotic Cell Cycle Ribosomal Subunit Export From Nucleus Cell Cycle Process Protein Localization To Chromatin Mitotic Nuclear Division Ribonucleoprotein Complex Biogenesis Cytoskeleton Organization Histone H2A Acetylation Cellular Localization Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Chromosome Segregation	Organelle Organization Cell Cycle Mitotic Cell Cycle Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Cellular Metabolic Process Mitotic Cell Cycle Process Cellular Process Response To Light Stimulus Response To Radiation Triglyceride Catabolic Process Gene Expression Positive Regulation Of Apoptotic Signaling Pathway Organelle Localization Acylglycerol Catabolic Process Endomembrane System Organization Establishment Of Organelle Localization Cell Cycle Process Positive Regulation Of Signal Transduction Peptidyl-lysine Modification Endosome Organization Protein Localization To Organelle Positive Regulation Of Metabolic Process Anatomical Structure Development System Development Regulation Of Signal Transduction Termination Of RNA Polymerase II Transcription Cytoplasmic Transport Programmed Cell Death Chromosome Organization Cell Division Ribosomal Subunit Export From Nucleus Cell Death Regulation Of Signaling Cellular Response To Stimulus Death Histone H3 Acetylation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Protein Ubiquitination Mitotic Nuclear Division Ribonucleoprotein Complex Biogenesis Response To Abiotic Stimulus Positive Regulation Of Striated Muscle Contraction Cellular Response To Organic Substance RNA Metabolic Process Organ Development Neurotransmitter Uptake
Tagcloud ?		1x apparatus consequences depicted digital dimerization disclosed dramatically facial filaments focused golgi half homology implies imported lis1 lish localization localizations motif mutated nucleus oligomerization participate prediction solved tbl1 transducin
Tagcloud (Difference) ?		1x apparatus consequences depicted digital dimerization disclosed dramatically facial filaments focused golgi half homology implies imported lis1 lish localization localizations motif mutated nucleus oligomerization participate prediction solved tbl1 transducin
Tagcloud (Intersection) ?