OFD1 and CCSER2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		OFD1	CCSER2
Description		OFD1 centriole and centriolar satellite protein	coiled-coil serine rich protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Membrane Motile Cilium Centriolar Satellite Ciliary Basal Body Cell Projection	Cytoplasm Cytoskeleton Microtubule Cytoskeleton
	Molecular Function	Protein Binding Identical Protein Binding Alpha-tubulin Binding Gamma-tubulin Binding Molecular Adaptor Activity	Protein Binding Microtubule Binding
	Biological Process	Mitotic Cell Cycle Centriole Replication Embryonic Body Morphogenesis Cell Projection Organization Axoneme Assembly Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Mitotic Spindle Assembly Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation	Microtubule Bundle Formation
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Hedgehog 'off' state Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases		Oral-facial-digital syndrome 1 Joubert syndrome
GWAS			Cerebrospinal P-tau181p levels ( 28247064) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Refractive error ( 32231278)
Interacting Genes		9 interacting genes: AKT1 CCSER2 CEP126 EIF6 GPRASP1 LUC7L2 NME7 RUVBL1 S100A6	12 interacting genes: APP ATRX CRADD EXOC1 EXOSC8 GTF2H1 KIFAP3 MAP1LC3B OFD1 PSMD11 STX1A TCEA2
Entrez ID		8481	54462
HPRD ID		02162	13832
Ensembl ID		ENSG00000046651	ENSG00000107771
Uniprot IDs		E9KL37 O75665	Q9H7U1
PDB IDs
Enriched GO Terms of Interacting Partners?			Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Protein-containing Complex Organization Axo-dendritic Transport Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Microtubule-based Transport Amylin Binding Endosome To Plasma Membrane Transport Vesicle Cellular Component Assembly Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Protein-containing Complex Assembly Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Modulation Of Excitatory Postsynaptic Potential Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Telomeric Post-embryonic Forelimb Morphogenesis Chromosome, Subtelomeric Region Vesicle Docking Involved In Exocytosis Membrane Docking Myosin Head/neck Binding Vesicle Docking Positive Regulation Of Norepinephrine Secretion Organelle Localization By Membrane Tethering Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Ciliary Basal Body Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Death Domain Binding Endopeptidase Complex U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Kinesin II Complex Positive Regulation Of Calcium-dependent Cell-cell Adhesion Calcium:proton Antiporter Activity Calcium Export From The Mitochondrion Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Microtubule-based Process Regulation Of Apoptotic Signaling Pathway
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