LIMK2 and ROCK1

  • Number of citations of the paper that reports this interaction (PMID 11018042)
  • 59
  • Data Source:
  • HPRD (in vitro, in vivo)

LIMK2

ROCK1

Gene Name LIM domain kinase 2 Rho-associated, coiled-coil containing protein kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Paclitaxel-induced neuropathy ( 23776197)
  • Type 2 diabetes nephropathy ( 21150874)
Protein-Protein Interactions 9 interactors: CDC42BPA CFL1 GSN HIPK3 HIST1H1A LIMK1 MBP PARD3 ROCK1 32 interactors: ADD1 ARHGAP24 C6orf165 CASP3 CASP7 CDC25A CDC34 CRMP1 DES DPYSL2 EZR FAM124A GFAP IKBKB IRS1 ITSN2 LIMK1 LIMK2 LMO2 MAGEB4 MSN PFN2 POLR3C PPP1R12A PTK2 RDX RHOA RHOC RND3 SMAD2 TSG101 VIM
Entrez ID 3985 6093
HPRD ID 03585 03414
Ensembl ID ENSG00000182541
Uniprot IDs E7EUC1 P53671 Q13464
PDB IDs 1X6A 1S1C 2ESM 2ETK 2ETR 2V55 3D9V 3NCZ 3NDM 3O0Z 3TV7 3TWJ 3V8S
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aberrant  cdk4  cofilin  cyclin  d1  death  downregulation  drp1  dynamic  effectors  epilepticus  fission  interacting  kip1  mediators  necrotic  neuronal  p27  programmed  rescue  rho  rock  se  subsequently  turn  unsuspected  upregulated  vulnerable 
angiogenic  au  contributor  decay  disperse  dispersion  ecs  eliciting  gtpase  herpesvirus  hsp27  kapb  kaposi  kaposin  ks  kshv  latently  likewise  mk2  p115rhogef  pb  pbs  reprogramming  restore  rhoa  ribonucleoprotein  sarcoma  secrete  secretory 
Tagcloud (Difference) ?
aberrant  cdk4  cofilin  cyclin  d1  death  downregulation  drp1  dynamic  effectors  epilepticus  fission  interacting  kip1  mediators  necrotic  neuronal  p27  programmed  rescue  rho  rock  se  subsequently  turn  unsuspected  upregulated  vulnerable 
angiogenic  au  contributor  decay  disperse  dispersion  ecs  eliciting  gtpase  herpesvirus  hsp27  kapb  kaposi  kaposin  ks  kshv  latently  likewise  mk2  p115rhogef  pb  pbs  reprogramming  restore  rhoa  ribonucleoprotein  sarcoma  secrete  secretory 
Tagcloud (Intersection) ?