PRRC2B and DDX31

		PRRC2B	DDX31
Description		proline rich coiled-coil 2B	DEAD-box helicase 31
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleolus Golgi Apparatus
	Molecular Function	RNA Binding Protein Binding	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity Isomerase Activity ATP Hydrolysis Activity
	Biological Process	Cell Differentiation	Ribosome Biogenesis
Pathways
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Lung function ( 31902109) Urate levels ( 31578528)
Interacting Genes		41 interacting genes: ALG13 ANKHD1 APP ATN1 ATXN1 ATXN1L BAG4 BCAS2 CRK CTBP1 DAPK1 DDX11 DIMT1 DMRTB1 DNAJC5 DPY30 EHMT2 ESS2 EXOSC1 EXOSC4 EXOSC7 FBXO7 IPO5 LSM5 MRPL44 NIP7 NXF1 NXF5 PRPF39 QKI RBFOX2 RBPMS RERE RPL13 SF1 SRPK2 SRSF4 TRNAU1AP TXNL4A YTHDF1 YTHDF3	1 interacting genes: RNF10
Entrez ID		84726	64794
HPRD ID		13805	10860
Ensembl ID		ENSG00000288701	ENSG00000125485
Uniprot IDs		Q5JSZ5 Q9BU62	A0AAK2PNZ4 Q9H8H2
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleus RNA Processing RNA Metabolic Process Nucleic Acid Binding RNA Splicing MRNA Metabolic Process Nucleolus MRNA Processing MRNA Binding Nucleoplasm Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Splicing, Via Transesterification Reactions Nucleolar Exosome (RNase Complex) Regulation Of MRNA Metabolic Process Cytoplasmic Stress Granule Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity Macromolecule Metabolic Process Regulation Of RNA Splicing Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Regulation Of MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing POZ Domain Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Stress Granule Assembly Negative Regulation Of Macromolecule Metabolic Process MRNA Splice Site Recognition Exoribonuclease Complex Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Spliceosomal Complex Nuclear RNA Export Factor Complex U4 SnRNA 3'-end Processing Protein-RNA Complex Assembly Cytoplasm Transcription Corepressor Activity Negative Regulation Of Metabolic Process Spliceosomal Complex Assembly Memory Negative Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Nuclear MRNA Surveillance Nuclear Inclusion Body N6-methyladenosine-containing RNA Reader Activity	Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Postsynapse To Nucleus Signaling Pathway Negative Regulation Of Schwann Cell Proliferation Extrinsic Component Of Postsynaptic Density Membrane Positive Regulation Of Myelination Negative Regulation Of Glial Cell Proliferation Regulation Of Glial Cell Proliferation Negative Regulation Of Gliogenesis Regulation Of Myelination Postsynaptic Signal Transduction Protein Monoubiquitination
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