ZNF69 and KATNAL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF69	KATNAL1
Description		zinc finger protein 69	katanin catalytic subunit A1 like 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Spindle Pole Cytoplasm Mitochondrion Centrosome Spindle Cytosol Cytoskeleton Microtubule Katanin Complex Microtubule Cytoskeleton Mitotic Spindle
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	Nucleotide Binding Protein Binding ATP Binding Microtubule Binding Microtubule Severing ATPase Activity Isomerase Activity ATP Hydrolysis Activity Identical Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Spermatogenesis Cytoplasmic Microtubule Organization Microtubule Severing
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494)	Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Blood osmolality (transformed sodium) ( 28360221) Fat distribution (HIV) ( 21897333) Femur bone mineral density x serum urate levels interaction ( 34046847) Male-pattern baldness ( 27182965) Rapid response to perioperative phenylephrine (change in mean arterial pressure) ( 33168928) Refractive error ( 32231278) Type 2 diabetes ( 31049640)
Interacting Genes		12 interacting genes: CFTR FAM124B FRS3 GTPBP3 KATNAL1 KRT31 LMNA LMO3 MEOX2 P4HB SMARCD1 ZNF417	18 interacting genes: AIRIM ASCC2 BYSL CEP57L1 CFTR COX17 CTNNA3 GCC1 GUCA1A IQUB KATNBL1 KLC4 MEOX2 PGAM2 PITPNC1 SIAH1 VPS4B ZNF69
Entrez ID		7620	84056
HPRD ID		11836	13753
Ensembl ID		ENSG00000198429	ENSG00000102781
Uniprot IDs		Q9UC07	B3KUK7 Q9BW62
PDB IDs			6B5C
Enriched GO Terms of Interacting Partners?		NBAF Complex RSC-type Complex NpBAF Complex GBAF Complex Nuclear Matrix Nucleosome Disassembly Protein-DNA Complex Disassembly Isomerase Activity Regulation Of Nucleotide-excision Repair SWI/SNF Complex Regulation Of G0 To G1 Transition Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Regulation Of Chromosome Organization Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Stem Cell Population Maintenance Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Myoblast Differentiation Positive Regulation Of Anion Channel Activity DNA Double-strand Break Attachment To Nuclear Envelope Epigenetic Regulation Of Gene Expression Structural Constituent Of Nuclear Lamina Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Procollagen-proline 4-dioxygenase Complex Regulation Of Stem Cell Population Maintenance Transcription Coactivator Activity Regulation Of Myoblast Differentiation Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway TRNA 5-taurinomethyluridine Synthase Activity Mitochondrial TRNA Wobble Uridine Modification Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Glucose Mediated Signaling Pathway Regulation Of Mitotic Metaphase/anaphase Transition ATP Hydrolysis Activity Positive Regulation Of Double-strand Break Repair Structural Constituent Of Cytoskeleton Positive Regulation Of Enamel Mineralization Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Peptidyl-proline Hydroxylation Regulation Of Sister Chromatid Segregation Regulation Of Glucose Mediated Signaling Pathway Transepithelial Water Transport Lamin Filament Nuclear Pore Localization Somite Specification Procollagen-proline 4-dioxygenase Activity Nucleosome Array Spacer Activity Positive Regulation Of T Cell Differentiation
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