TBC1D3G and GTPBP3

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		TBC1D3G	GTPBP3
Name		TBC1 domain family member 3G	GTP binding protein 3, mitochondrial
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Membrane	Nucleus Cytoplasm Mitochondrion Transferase Complex
	Molecular Function	GTPase Activator Activity Protein Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity TRNA 5-taurinomethyluridine Synthase Activity
	Biological Process	None	TRNA Wobble Uridine Modification TRNA Modification TRNA Processing TRNA Methylation Mitochondrial TRNA Wobble Uridine Modification
Pathways		None	tRNA modification in the mitochondrion
GWAS		Blood protein levels ( 23696881 ) Body mass index ( 26426971 )	Mitochondrial DNA copy number ( 30704525 )
Interacting Genes		8 interacting genes: BAG3 BAG4 GEM GRB2 GTPBP3 MDFI PSMD2 ZRANB1	29 interacting genes: BEND7 CAPN3 CCDC32 CIC COPS5 DCAF8 DPPA4 GNE INCA1 ITGB3BP MBD3L1 MEOX2 MESD OGT PARP11 PFKL POLDIP3 PPP1R18 PRPF3 PTAFR RALY RIBC2 SERTAD3 SINHCAF TBC1D3B TBC1D3G ZFP90 ZNF69 ZNF774
Entrez ID		101060321	84705
HPRD ID		Not available	12255
Ensembl ID		ENSG00000260287	ENSG00000130299
Uniprot IDs		Q6DHY5 Q6IPX1	B7Z563 Q969Y2
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Negative Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Adenyl-nucleotide Exchange Factor Activity Positive Regulation Of Actin Filament Polymerization Regulation Of Protein Targeting To Mitochondrion Nucleus Guanyl-nucleotide Exchange Factor Adaptor Activity Negative Regulation Of MRNA Modification Positive Regulation Of Protein Polymerization Grb2-EGFR Complex Proteasome Storage Granule Protein-folding Chaperone Binding Autophagosome Organization Autophagosome Assembly TRNA 5-taurinomethyluridine Synthase Activity Mitochondrial TRNA Wobble Uridine Modification Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Negative Regulation Of Establishment Of Protein Localization Protein K29-linked Deubiquitination Positive Regulation Of Aggrephagy Protein K33-linked Deubiquitination Positive Regulation Of Supramolecular Fiber Organization Neurotrophin TRKA Receptor Binding Vacuole Organization Aggresome Assembly Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process	None