TRIM46 and AK5

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TRIM46	AK5
Gene Name		tripartite motif containing 46	adenylate kinase 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular	Cytoplasm Microtubule Organizing Center Cytosol
	Molecular Function	Zinc Ion Binding	Adenylate Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding Nucleoside Kinase Activity
	Biological Process		Nucleoside Diphosphate Phosphorylation ADP Biosynthetic Process DADP Biosynthetic Process Nucleoside Triphosphate Biosynthetic Process Pyrimidine Ribonucleotide Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Small Molecule Metabolic Process ATP Metabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system	Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS		Urate levels ( 23263486)
Protein-Protein Interactions		17 interactors: AK5 BRCA1 CBLC MDM4 OTUD6A RNF125 RNF7 TK1 TRIM9 TSG101 UBE2U UBE2Z UCHL5 USP1 USP15 USP2 USP32	7 interactors: C7orf26 CPNE6 NUCKS1 RNF114 STRN4 TRIM46 UGDH
Entrez ID		80128	26289
HPRD ID		15563	10472
Ensembl ID		ENSG00000163462	ENSG00000154027
Uniprot IDs		B7Z3S2 B7Z4F9 F5GYK0 Q7Z4K8	Q9Y6K8
PDB IDs			2BWJ
Enriched GO Terms of Interacting Partners?		Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Protein Deubiquitination Protein Modification By Small Protein Removal Cellular Protein Modification Process Cellular Macromolecule Catabolic Process Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Metabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Protein Metabolic Process Catabolic Process Cellular Metabolic Process Monoubiquitinated Protein Deubiquitination Regulation Of Protein Metabolic Process Regulation Of Proteolysis Cellular Response To DNA Damage Stimulus Regulation Of Cellular Protein Metabolic Process Protein Polyubiquitination Cellular Response To Stress DNA Metabolic Process DNA Repair Positive Regulation Of Histone H4-K20 Methylation Fetal Process Involved In Parturition DADP Biosynthetic Process Positive Regulation Of Histone H4-K16 Acetylation Regulation Of DNA Repair Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Metabolic Process G0 To G1 Transition Skeletal Muscle Cell Proliferation Positive Regulation Of Histone H3-K9 Acetylation Histone H2B Conserved C-terminal Lysine Deubiquitination Protein K27-linked Deubiquitination Negative Regulation Of SNARE Complex Assembly DNA Damage Response, Signal Transduction By P53 Class Mediator Protein Stabilization Signal Transduction In Response To DNA Damage Regulation Of Cell Cycle Arrest Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Protein K33-linked Deubiquitination Protein K29-linked Deubiquitination	UDP-glucuronate Biosynthetic Process UDP-glucuronate Metabolic Process
Tagcloud ?		a1cf activins acvr1b acvrl1 ancestry atxn2 b3gnt4 baz1b consortium excretion fractional gout gugc hlf hnf4g implicate inhbb inhibins maf nfat5 painful prkag2 replicated sfmbt1 stc1 tmem171 ube2q2 urate vegfa
Tagcloud (Difference) ?		a1cf activins acvr1b acvrl1 ancestry atxn2 b3gnt4 baz1b consortium excretion fractional gout gugc hlf hnf4g implicate inhbb inhibins maf nfat5 painful prkag2 replicated sfmbt1 stc1 tmem171 ube2q2 urate vegfa
Tagcloud (Intersection) ?