IL1F10 and IL1R1

Number of citations of the paper that reports this interaction (PMID 11278614)
13

Data Source:
HPRD (in vitro)

		IL1F10	IL1R1
Gene Name		interleukin 1 family, member 10 (theta)	interleukin 1 receptor, type I
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane
	Molecular Function	Cytokine Activity Interleukin-1 Receptor Binding	Protease Binding Signal Transducer Activity Transmembrane Signaling Receptor Activity Interleukin-1 Receptor Activity Interleukin-1, Type I, Activating Receptor Activity Platelet-derived Growth Factor Receptor Binding Protein Binding
	Biological Process	Cytokine-mediated Signaling Pathway	Immune Response Cell Surface Receptor Signaling Pathway Regulation Of Inflammatory Response Interleukin-1-mediated Signaling Pathway Response To Interleukin-1
Pathways			Signaling by Interleukins Cytokine Signaling in Immune system Interleukin-1 signaling
Drugs			Anakinra
Diseases
GWAS		C-reactive protein ( 21300955 22939635)	Asthma ( 22561531) Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		1 interactors: IL1R1	11 interactors: IL1A IL1B IL1F10 IL1RAP IL1RN IRAK2 MYD88 PIK3R1 SIGIRR TICAM2 TOLLIP
Entrez ID		84639	3554
HPRD ID		17144	00994
Ensembl ID		ENSG00000136697	ENSG00000115594
Uniprot IDs		Q8WWZ1	P14778
PDB IDs			1G0Y 1IRA 1ITB 4DEP 4GAF
Enriched GO Terms of Interacting Partners?		Interleukin-1-mediated Signaling Pathway Cellular Response To Interleukin-1 Response To Interleukin-1	Inflammatory Response Defense Response Response To Cytokine Immune Response Fever Generation Heat Generation Acute-phase Response Cellular Response To Organic Substance Regulation Of Chemokine Production Cytokine-mediated Signaling Pathway Immune System Process Acute Inflammatory Response Response To Stress Regulation Of Cytokine Production Response To Organic Substance Regulation Of Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Regulation Of Cytokine Biosynthetic Process Signaling Response To Lipopolysaccharide Temperature Homeostasis Cell Communication Positive Regulation Of JNK Cascade Response To Molecule Of Bacterial Origin Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Cytokine Production Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Signal Transduction Cellular Response To Lipopolysaccharide Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Cellular Response To Molecule Of Bacterial Origin Regulation Of JNK Cascade Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Chemokine Production Cellular Response To Stimulus Positive Regulation Of MAPK Cascade Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Stress-activated MAPK Cascade Response To Bacterium Signal Transduction Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Interleukin-6 Production Positive Regulation Of Cytokine Biosynthetic Process Regulation Of Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of Immune Response Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Protein Metabolic Process Positive Regulation Of Chemokine Biosynthetic Process
Tagcloud ?		ameliorate begin ccl2 ccl20 ccl28 ccl3 ccl4 ccl8 cd40lg cd47 cxcl1 cxcl12 cxcl13 gdf10 gdf3 il17f il1f5 metalloproteinase mmp1 mmp13 mmp16 mmp7 mmps phosflow polymeric polyvinyl pvc tgfbeta3 tnfsf10	a2 cdk2 cyclin depleting depletion diminish dst emerging endogenous extra fkbp5 hef1 investigates isoform measuring p21 p27 pr predominantly progesterone progestin q regulating repressed repression sgk1 t47d target tethering
Tagcloud (Difference) ?		ameliorate begin ccl2 ccl20 ccl28 ccl3 ccl4 ccl8 cd40lg cd47 cxcl1 cxcl12 cxcl13 gdf10 gdf3 il17f il1f5 metalloproteinase mmp1 mmp13 mmp16 mmp7 mmps phosflow polymeric polyvinyl pvc tgfbeta3 tnfsf10	a2 cdk2 cyclin depleting depletion diminish dst emerging endogenous extra fkbp5 hef1 investigates isoform measuring p21 p27 pr predominantly progesterone progestin q regulating repressed repression sgk1 t47d target tethering
Tagcloud (Intersection) ?