IL1R1 and IL1F10

Number of citations of the paper that reports this interaction (PMID 11278614)
13

Data Source:
HPRD (in vitro)

		IL1R1	IL1F10
Gene Name		interleukin 1 receptor, type I	interleukin 1 family, member 10 (theta)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane	Extracellular Space
	Molecular Function	Protease Binding Signal Transducer Activity Transmembrane Signaling Receptor Activity Interleukin-1 Receptor Activity Interleukin-1, Type I, Activating Receptor Activity Platelet-derived Growth Factor Receptor Binding Protein Binding	Cytokine Activity Interleukin-1 Receptor Binding
	Biological Process	Immune Response Cell Surface Receptor Signaling Pathway Regulation Of Inflammatory Response Interleukin-1-mediated Signaling Pathway Response To Interleukin-1	Cytokine-mediated Signaling Pathway
Pathways		Signaling by Interleukins Cytokine Signaling in Immune system Interleukin-1 signaling
Drugs		Anakinra
Diseases
GWAS		Asthma ( 22561531) Inflammatory bowel disease ( 23128233)	C-reactive protein ( 21300955 22939635)
Protein-Protein Interactions		11 interactors: IL1A IL1B IL1F10 IL1RAP IL1RN IRAK2 MYD88 PIK3R1 SIGIRR TICAM2 TOLLIP	1 interactors: IL1R1
Entrez ID		3554	84639
HPRD ID		00994	17144
Ensembl ID		ENSG00000115594	ENSG00000136697
Uniprot IDs		P14778	Q8WWZ1
PDB IDs		1G0Y 1IRA 1ITB 4DEP 4GAF
Enriched GO Terms of Interacting Partners?		Inflammatory Response Defense Response Response To Cytokine Immune Response Fever Generation Heat Generation Acute-phase Response Cellular Response To Organic Substance Regulation Of Chemokine Production Cytokine-mediated Signaling Pathway Immune System Process Acute Inflammatory Response Response To Stress Regulation Of Cytokine Production Response To Organic Substance Regulation Of Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Regulation Of Cytokine Biosynthetic Process Signaling Response To Lipopolysaccharide Temperature Homeostasis Cell Communication Positive Regulation Of JNK Cascade Response To Molecule Of Bacterial Origin Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Cytokine Production Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Signal Transduction Cellular Response To Lipopolysaccharide Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Cellular Response To Molecule Of Bacterial Origin Regulation Of JNK Cascade Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Chemokine Production Cellular Response To Stimulus Positive Regulation Of MAPK Cascade Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Stress-activated MAPK Cascade Response To Bacterium Signal Transduction Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Interleukin-6 Production Positive Regulation Of Cytokine Biosynthetic Process Regulation Of Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of Immune Response Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Protein Metabolic Process Positive Regulation Of Chemokine Biosynthetic Process	Interleukin-1-mediated Signaling Pathway Cellular Response To Interleukin-1 Response To Interleukin-1
Tagcloud ?		a2 cdk2 cyclin depleting depletion diminish dst emerging endogenous extra fkbp5 hef1 investigates isoform measuring p21 p27 pr predominantly progesterone progestin q regulating repressed repression sgk1 t47d target tethering	ameliorate begin ccl2 ccl20 ccl28 ccl3 ccl4 ccl8 cd40lg cd47 cxcl1 cxcl12 cxcl13 gdf10 gdf3 il17f il1f5 metalloproteinase mmp1 mmp13 mmp16 mmp7 mmps phosflow polymeric polyvinyl pvc tgfbeta3 tnfsf10
Tagcloud (Difference) ?		a2 cdk2 cyclin depleting depletion diminish dst emerging endogenous extra fkbp5 hef1 investigates isoform measuring p21 p27 pr predominantly progesterone progestin q regulating repressed repression sgk1 t47d target tethering	ameliorate begin ccl2 ccl20 ccl28 ccl3 ccl4 ccl8 cd40lg cd47 cxcl1 cxcl12 cxcl13 gdf10 gdf3 il17f il1f5 metalloproteinase mmp1 mmp13 mmp16 mmp7 mmps phosflow polymeric polyvinyl pvc tgfbeta3 tnfsf10
Tagcloud (Intersection) ?