MAK16 and FRMD6

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		MAK16	FRMD6
Description		MAK16 homolog	FERM domain containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Preribosome, Large Subunit Precursor	Cytoplasm Plasma Membrane Membrane Apical Junction Complex Cytoplasmic Side Of Apical Plasma Membrane
	Molecular Function	RNA Binding Protein Binding	Protein Binding
	Biological Process	Maturation Of 5.8S RRNA Maturation Of LSU-rRNA	Apical Constriction Intracellular Protein Localization Regulation Of Actin Filament-based Process Positive Regulation Of Hippo Signaling
Pathways
Drugs
Diseases
GWAS		Pulse pressure ( 30224653)	Anticoagulant levels ( 22216198) Brain structure ( 20171287) Cognitive decline rate in late mild cognitive impairment ( 26252872) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hippocampal atrophy ( 19668339) Lung cancer (smoking interaction) ( 24658283) Multiple sclerosis ( 31604244) Nonsyndromic cleft lip with or without cleft palate ( 28087736) Total ventricular volume ( 21116278) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		3 interacting genes: CSNK2A1 FRMD6 LIN7B	27 interacting genes: - BLZF1 COX6B2 DNAJA3 EXOC5 GMCL1 HMBOX1 IKZF1 JMJD6 LZTS2 MAK16 MED4 MID2 MLH1 NKAPD1 PARD6B RASSF8 SSX2IP SUV39H1 SYT17 TCF12 TLK2 TRIM55 TRIM63 TSC22D4 WDR7 YWHAB
Entrez ID		84549	122786
HPRD ID		15223	12646
Ensembl ID		ENSG00000198042	ENSG00000139926
Uniprot IDs		Q9BXY0	Q96NE9
PDB IDs		8FKP 8FKR 8FKT 8FKV
Enriched GO Terms of Interacting Partners?		Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Aggrephagy MPP7-DLG1-LIN7 Complex Cytoplasmic Side Of Apical Plasma Membrane Apical Constriction Intracellular Protein Localization Aggrephagy Double-strand Break Repair Via Classical Nonhomologous End Joining Protein Targeting To Vacuole Involved In Autophagy Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Regulation Of Synaptic Assembly At Neuromuscular Junction MRNA Methylguanosine-cap Decapping Regulation Of Growth RNA Decapping Positive Regulation Of Hippo Signaling Sin3-type Complex PcG Protein Complex Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Execution Phase Of Apoptosis Protein Localization To Site Of Double-strand Break Apical Junction Complex
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