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C11orf58 and POLR2C
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
0
Data Source:
BioGRID
(two hybrid)
C11orf58
POLR2C
Description
chromosome 11 open reading frame 58
RNA polymerase II subunit C
Image
No pdb structure
GO Annotations
Cellular Component
Cellular_component
DNA-directed RNA Polymerase Complex
Nucleus
Nucleoplasm
RNA Polymerase II, Core Complex
Cytosol
Molecular Function
Molecular_function
DNA Binding
DNA-directed RNA Polymerase Activity
Protein Binding
Protein Dimerization Activity
Biological Process
Biological_process
DNA-templated Transcription
Transcription By RNA Polymerase II
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
MicroRNA (miRNA) biogenesis
Transcriptional regulation by small RNAs
PIWI-interacting RNA (piRNA) biogenesis
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS
Chronotype (
30696823
)
Coronary artery disease (
33020668
)
Femoral neck bone mineral density (
29499414
)
Heel bone mineral density (
28869591
30598549
)
High light scatter reticulocyte count (
27863252
32888494
)
High light scatter reticulocyte percentage of red cells (
27863252
32888494
)
Lumbar spine bone mineral density (
29499414
)
Mean corpuscular hemoglobin (
27863252
)
Mean corpuscular volume (
27863252
)
Mean spheric corpuscular volume (
32888494
)
Red blood cell count (
32888494
)
Reticulocyte count (
27863252
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Serum alkaline phosphatase levels (
33547301
)
Interacting Genes
17 interacting genes:
A2M
CEBPA
CEP126
EEF1G
FBN3
MBTPS1
POLR2C
PTN
RNF19A
RPLP1
SEMA5B
SF3B1
SHC1
SLC44A1
SNCAIP
TRA2A
ZBTB48
32 interacting genes:
ATF4
ATF7IP
C11orf58
CCHCR1
EEF1A1
ERG28
ITCH
LRIF1
MYOG
NECAB2
NEDD4
NFKBIA
NUDT21
OTUD5
POLR2A
POLR2B
POLR2D
POLR2E
POLR2F
POLR2G
POLR2H
POLR2J
POLR2J2
POLR2K
POLR2L
RPAP1
RSPH1
SMARCC2
STC2
TAF15
UBC
UBE2W
Entrez ID
10944
5432
HPRD ID
18069
15945
Ensembl ID
ENSG00000110696
ENSG00000102978
Uniprot IDs
O00193
P19387
Q6FGR6
PDB IDs
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6DRD
6O9L
6XRE
7LBM
9EHZ
9EI1
9EI3
9EI4
Enriched GO Terms of Interacting Partners
?
RNA Polymerase II, Core Complex
DNA-directed RNA Polymerase Complex
DNA-directed RNA Polymerase Activity
Transcription By RNA Polymerase II
DNA-templated Transcription
RNA Polymerase I Complex
RNA Polymerase III Complex
Nucleobase-containing Compound Biosynthetic Process
Macromolecule Biosynthetic Process
Nucleus
RNA Metabolic Process
Nucleoplasm
Nucleic Acid Metabolic Process
Transcription By RNA Polymerase III
TRNA Transcription By RNA Polymerase III
TRNA Transcription
Nucleobase-containing Compound Metabolic Process
RNA-directed RNA Polymerase Activity
RNA-templated Transcription
Macromolecule Metabolic Process
DNA Binding
Regulation Of Transcription By RNA Polymerase I
5'-3' RNA Polymerase Activity
Protein Monoubiquitination
Nucleolus
Transcription By RNA Polymerase I
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Nucleotidyltransferase Activity
Translation Initiation Factor Binding
Negative Regulation Of Gene Expression
Negative Regulation Of Potassium Ion Transport
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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