PCGF5 and RING1

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		PCGF5	RING1
Gene Name		polycomb group ring finger 5	ring finger protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Centrosome PcG Protein Complex	Sex Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Speck PcG Protein Complex PRC1 Complex
	Molecular Function	Protein Binding Zinc Ion Binding	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Transcription, DNA-templated Anterior/posterior Pattern Specification Histone H2A Monoubiquitination Negative Regulation Of Transcription, DNA-templated Camera-type Eye Morphogenesis
Pathways			Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS			Wegener's granulomatosis ( 23740775)
Protein-Protein Interactions		11 interactors: BCOR CBX6 CBX7 CBX8 PCGF1 PHC2 PRMT6 RING1 RNF2 TRAF2 TRIM8	31 interactors: APP BMI1 CBX4 CBX6 CBX7 CBX8 E2F6 ELAC2 FBXO38 FHL1 HIST3H3 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 PHC1 PIK3R3 RB1 RNF2 RYBP UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K USP7 YAF2
Entrez ID		84333	6015
HPRD ID		17825	03624
Ensembl ID		ENSG00000180628	ENSG00000204227
Uniprot IDs		Q86SE9	Q06587
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone Ubiquitination Histone H2A Monoubiquitination Histone H2A Ubiquitination Chromatin Modification Chromatin Organization Histone Monoubiquitination Protein Ubiquitination Chromosome Organization Protein Modification By Small Protein Conjugation Protein Monoubiquitination Negative Regulation Of RNA Biosynthetic Process Histone Modification Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Gene Expression RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Organelle Organization RNA Metabolic Process Cellular Protein Modification Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Histone H3-K36 Methylation Nitrogen Compound Metabolic Process Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Histone H3-R2 Methylation Negative Regulation Of Tooth Mineralization Histone H2A-K119 Monoubiquitination Pattern Specification Process Axis Specification Cellular Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity	Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein K48-linked Ubiquitination Histone Ubiquitination Chromatin Modification Chromatin Organization Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Polyubiquitination Negative Regulation Of Gene Expression Transcription, DNA-templated Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process RNA Metabolic Process Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Histone Modification Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Protein Monoubiquitination Nucleobase-containing Compound Metabolic Process Cellular Protein Modification Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Histone Monoubiquitination Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Protein K11-linked Ubiquitination Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Mitotic Cell Cycle Phase Transition Histone H2A Monoubiquitination Regulation Of Cell Cycle Phase Transition Cellular Protein Metabolic Process Regulation Of Metabolic Process Histone H2A Ubiquitination Organelle Organization Metabolic Process Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Proteasomal Protein Catabolic Process
Tagcloud ?		actg1 adaptin bacterium caenorhabditis cap1 chaffeensis colocalized cored cotransformation cox2 ehrlichia evading gga1 host igl igll1 morulae obligately phagocytes reconstitute reprogram survives tr tropism trp120 trp47 trps unc unc13d	4h accomplish antioxidant ck cmv cortex creatine de dehydrogenase downregulated e3 electrophoresis extremely finger hselm lactate ldh ligase nontg secretase sel selenium selenoprotein selm spots synaptotagmin sytxv tg upregulated
Tagcloud (Difference) ?		actg1 adaptin bacterium caenorhabditis cap1 chaffeensis colocalized cored cotransformation cox2 ehrlichia evading gga1 host igl igll1 morulae obligately phagocytes reconstitute reprogram survives tr tropism trp120 trp47 trps unc unc13d	4h accomplish antioxidant ck cmv cortex creatine de dehydrogenase downregulated e3 electrophoresis extremely finger hselm lactate ldh ligase nontg secretase sel selenium selenoprotein selm spots synaptotagmin sytxv tg upregulated
Tagcloud (Intersection) ?