BTBD10 and LAMA5

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		BTBD10	LAMA5
Description		BTB domain containing 10	laminin subunit alpha 5
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm	Extracellular Region Basement Membrane Laminin-5 Complex Extracellular Space Nucleus Extracellular Matrix Neuromuscular Junction Synaptic Cleft Laminin-10 Complex Laminin-11 Complex Extracellular Exosome Extracellular Matrix Of Synaptic Cleft Glutamatergic Synapse
	Molecular Function	Protein Binding	Signaling Receptor Binding Integrin Binding Extracellular Matrix Structural Constituent Receptor Ligand Activity Cell Adhesion Mediator Activity
	Biological Process	Type B Pancreatic Cell Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction	Branching Involved In Ureteric Bud Morphogenesis Morphogenesis Of A Polarized Epithelium Neural Crest Cell Migration Kidney Development Hair Follicle Development Cell Adhesion Integrin-mediated Signaling Pathway Muscle Organ Development Animal Organ Morphogenesis Morphogenesis Of Embryonic Epithelium Cell Migration Regulation Of Cell Adhesion Lung Development Regulation Of Cell Migration Substrate Adhesion-dependent Cell Spreading Trunk Neural Crest Cell Migration Odontogenesis Of Dentin-containing Tooth Regulation Of Embryonic Development Skeletal System Morphogenesis System Development Branching Morphogenesis Of An Epithelial Tube Regulation Of Epithelial Cell Proliferation Cilium Assembly Branching Involved In Salivary Gland Morphogenesis Protein Localization To Plasma Membrane Postsynapse Organization
Pathways			Degradation of the extracellular matrix Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans Interleukin-4 and Interleukin-13 signaling MET activates PTK2 signaling Attachment of bacteria to epithelial cells Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC) Developmental Lineage of Pancreatic Ductal Cells
Drugs			Lanoteplase
Diseases
GWAS		Progression free survival in serous epithelial ovarian cancer treated with carboplatin and paclitaxel ( 28935272)	Colorectal cancer ( 20972440 24737748 25990418) Colorectal cancer or advanced adenoma ( 30510241) Estimated glomerular filtration rate ( 31152163) Femur bone mineral density x serum urate levels interaction ( 34046847) Neuroblastoma (pediatric) ( 32599975) Pelvic organ prolapse ( 26545240) Plateletcrit ( 32888494) Prostate cancer ( 23535732)
Interacting Genes		8 interacting genes: ACIN1 CDC37 CUL3 DLG5 LAMA5 MAPK3 PPP1CA PPP1CC	16 interacting genes: ATF7IP BCAM BTBD10 COL7A1 CRKL DAG1 FBLN2 HOXA1 LAMC1 MEP1A MTDH MYOC SMAD2 SV2A UBC USP4
Entrez ID		84280	3911
HPRD ID		17045	03020
Ensembl ID		ENSG00000148925	ENSG00000130702
Uniprot IDs		B7Z503 D3DQW7 Q9BSF8	O15230
PDB IDs			5XAU 7CEC
Enriched GO Terms of Interacting Partners?		Glutamatergic Synapse PTW/PP1 Phosphatase Complex Regulation Of Protein Stability Branching Morphogenesis Of An Epithelial Tube Morphogenesis Of A Branching Structure Morphogenesis Of A Branching Epithelium Entrainment Of Circadian Clock By Photoperiod Protein Phosphatase 1 Binding Photoperiodism Entrainment Of Circadian Clock Postsynapse Protein Stabilization Postsynapse Organization Anatomical Structure Morphogenesis Animal Organ Development Transcription Elongation By RNA Polymerase II Organelle Organization Tube Morphogenesis DNA-templated Transcription Elongation Regulation Of Cell Population Proliferation Morphogenesis Of An Epithelium Circadian Regulation Of Gene Expression Glycogen Metabolic Process Chromosome Organization Cellular Response To Amino Acid Starvation Negative Regulation Of TORC1 Signaling Response To Amino Acid Starvation Energy Reserve Metabolic Process Polysaccharide Metabolic Process Regulation Of Multicellular Organismal Process Phosphatase Activity Embryonic Morphogenesis Extracellular Matrix Of Synaptic Cleft Tissue Morphogenesis Integrin-mediated Signaling Pathway DNA-templated Transcription Protein Dephosphorylation RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Protein Serine/threonine Phosphatase Activity Cell Division Negative Regulation Of TOR Signaling Regulation Of TORC1 Signaling Positive Regulation Of Macroautophagy Trophectodermal Cellular Morphogenesis Liver Morphogenesis Zonula Adherens Assembly HSP90-CDC37 Chaperone Complex Lung Development Positive Regulation Of Cellular Component Organization Glial Cell Differentiation	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Positive Regulation Of Signal Transduction Regulation Of Cell-substrate Adhesion Extracellular Matrix Constituent Conferring Elasticity Basement Membrane Positive Regulation Of Cell Adhesion Positive Regulation Of Cell Communication Positive Regulation Of Signaling Myelination In Peripheral Nervous System Node Of Ranvier Laminin Binding Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Response To Cholesterol Extracellular Space Cell-substrate Adhesion Endoderm Development Positive Regulation Of Intracellular Signal Transduction Collagen Type VII Trimer Regulation Of Cell Adhesion RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Muscle Attachment Semicircular Canal Formation Skeletal Muscle Hypertrophy Adenosine Receptor Binding Regulation Of Signal Transduction Neuron Projection Development Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Extracellular Region Endoplasmic Reticulum Lumen Heart Development Helper T Cell Diapedesis Chordate Pharynx Development Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Cell Communication Cerebellar Neuron Development Regulation Of Intracellular Signal Transduction Receptor Tyrosine Kinase Binding Neuromuscular Junction Regulation Of Signaling Response To Transforming Growth Factor Beta Retrograde Trans-synaptic Signaling By Trans-synaptic Protein Complex Nerve Maturation Positive Regulation Of Cell-matrix Adhesion Calcium-dependent Cell-matrix Adhesion Peptide Hormone Secretion Endothelin B Receptor Binding Peptide Secretion Abducens Nerve Formation
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