LAMA5 and BTBD10

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		LAMA5	BTBD10
Gene Name		laminin, alpha 5	BTB (POZ) domain containing 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Basement Membrane Basal Lamina Laminin-1 Complex Laminin-5 Complex Extracellular Space Nucleus Extracellular Matrix Laminin-10 Complex Laminin-11 Complex Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	Integrin Binding Structural Molecule Activity
	Biological Process	Angiogenesis Branching Involved In Ureteric Bud Morphogenesis Morphogenesis Of A Polarized Epithelium Neural Crest Cell Migration Hair Follicle Development Cytoskeleton Organization Integrin-mediated Signaling Pathway Muscle Organ Development Cell Recognition Cell Proliferation Embryo Development Morphogenesis Of Embryonic Epithelium Cell Migration Extracellular Matrix Disassembly Cell Differentiation Regulation Of Cell Adhesion Extracellular Matrix Organization Lung Development Regulation Of Cell Migration Substrate Adhesion-dependent Cell Spreading Regulation Of Cell Proliferation Cilium Assembly Odontogenesis Of Dentin-containing Tooth Endothelial Cell Differentiation Regulation Of Embryonic Development Focal Adhesion Assembly Branching Involved In Salivary Gland Morphogenesis Establishment Of Protein Localization To Plasma Membrane	Positive Regulation Of Phosphorylation Type B Pancreatic Cell Proliferation Negative Regulation Of Neuron Death
Pathways		Laminin interactions ECM proteoglycans Non-integrin membrane-ECM interactions Degradation of the extracellular matrix
Drugs
Diseases
GWAS		Colorectal cancer ( 20972440) Prostate cancer ( 23535732)
Protein-Protein Interactions		15 interactors: ATF7IP BCAM BTBD10 COL7A1 CRKL DAG1 FBLN2 LAMC1 MEP1A MYOC PLAT PLG SMAD2 SV2A USP4	8 interactors: ACIN1 CDC37 CUL3 DLG5 LAMA5 MAPK3 PPP1CA PPP1CC
Entrez ID		3911	84280
HPRD ID		03020	17045
Ensembl ID		ENSG00000130702	ENSG00000148925
Uniprot IDs		O15230	B7Z228 D3DQW7 Q6P5W1 Q9BSF8
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Endoderm Development Extracellular Matrix Disassembly Fibrinolysis Regulation Of Cell-substrate Adhesion Cell-substrate Adhesion Myelination In Peripheral Nervous System Schwann Cell Development Negative Regulation Of Cell-substrate Adhesion Endoderm Formation Negative Regulation Of Blood Coagulation Schwann Cell Differentiation Negative Regulation Of Coagulation Nerve Maturation Skeletal Muscle Hypertrophy ERBB2-ERBB3 Signaling Pathway Negative Regulation Of Wound Healing Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Calcium-dependent Cell-matrix Adhesion ERBB2 Signaling Pathway Glial Cell Development Regulation Of Blood Coagulation Proteolysis Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Positive Regulation Of Ovulation Mononuclear Cell Migration Zygotic Specification Of Dorsal/ventral Axis Peripheral Nervous System Development Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Fibrinolysis Positive Regulation Of Cell-substrate Adhesion Regulation Of Protein Kinase B Signaling Formation Of Primary Germ Layer Regulation Of Wound Healing Tissue Development Myelination Regulation Of Cellular Process Positive Regulation Of Mesoderm Development Non-canonical Wnt Signaling Pathway Via JNK Cascade Primary MiRNA Processing Axon Ensheathment Regulation Of Nodal Signaling Pathway Non-canonical Wnt Signaling Pathway Via MAPK Cascade Common-partner SMAD Protein Phosphorylation Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Activin Receptor Signaling Pathway	Triglyceride Catabolic Process Entrainment Of Circadian Clock By Photoperiod Morphogenesis Of A Polarized Epithelium Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Branching Morphogenesis Of An Epithelial Tube Morphogenesis Of A Branching Epithelium Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Lung Development Morphogenesis Of A Branching Structure Respiratory Tube Development Respiratory System Development Adherens Junction Assembly Glycogen Metabolic Process Epithelial Tube Morphogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cell Division Circadian Regulation Of Gene Expression Tube Morphogenesis Polysaccharide Metabolic Process Zonula Adherens Assembly Negative Regulation Of Apolipoprotein Binding Adherens Junction Organization Triglyceride Metabolic Process Regulation Of Circadian Rhythm Anatomical Structure Morphogenesis Morphogenesis Of An Epithelium Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Neutral Lipid Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Cell Cycle Cellular Response To Growth Factor Stimulus Integrin-mediated Signaling Pathway Response To Growth Factor Regulation Of Signal Transduction Energy Reserve Metabolic Process Trophectodermal Cellular Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Tissue Morphogenesis Cellular Lipid Catabolic Process Multicellular Organismal Development Organ Development Protein Localization To Adherens Junction Regulation Of Golgi Inheritance Tube Development Cell Morphogenesis Involved In Differentiation Circadian Rhythm
Tagcloud ?		anencephaly aperta arches axd bifida breadth cart1 curly ectoderm exencephaly faulty floorplate folds gja1 jmj macs mlp neuroepithelial neuroepithelium nonsyndromic notochord ntds occulta rachischisis rostro selh spina tcfap2a terc	aggregates als amyotrophic apparatus cords dismutase fragmentation g93a ga golgi horn immunoreactivity immunostained mirror morphology neuron paraffin polyclonal poz ptdp sections sod1 spinal sporadic superoxide suppresses tar tgn
Tagcloud (Difference) ?		anencephaly aperta arches axd bifida breadth cart1 curly ectoderm exencephaly faulty floorplate folds gja1 jmj macs mlp neuroepithelial neuroepithelium nonsyndromic notochord ntds occulta rachischisis rostro selh spina tcfap2a terc	aggregates als amyotrophic apparatus cords dismutase fragmentation g93a ga golgi horn immunoreactivity immunostained mirror morphology neuron paraffin polyclonal poz ptdp sections sod1 spinal sporadic superoxide suppresses tar tgn
Tagcloud (Intersection) ?