POLR3GL and YAF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		POLR3GL	YAF2
Description		RNA polymerase III subunit GL	YY1 associated factor 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm RNA Polymerase III Complex Cytosol	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Transcription By RNA Polymerase III	Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		10 interacting genes: BEND7 CCND3 LMO1 M1AP MEOX1 MEOX2 PAX6 RBPMS TFCP2 YAF2	28 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 PTEN SETBP1 SPANXN2 SPANXN3 TLK1 UBC XAGE1B YY1 ZFP42
Entrez ID		84265	10138
HPRD ID		14546	09606
Ensembl ID		ENSG00000121851	ENSG00000015153
Uniprot IDs		A6NGX6 Q9BT43	B4DJQ9 G3V212 Q8IY57
PDB IDs		5AFQ	2D9G
Enriched GO Terms of Interacting Partners?		Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Somite Specification Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Segment Specification HMG Box Domain Binding Somite Development Regulation Of RNA Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Sequence-specific Double-stranded DNA Binding Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity Positive Regulation Of Macromolecule Metabolic Process Transcription Coactivator Activity Embryonic Pattern Specification DNA Binding Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Male Meiosis Chromosome Separation Regulation Of Gene Expression Positive Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Cyclin D3-CDK6 Complex Regulation Of Transcription By RNA Polymerase II Cyclin D3-CDK4 Complex Pattern Specification Process Regulation Of T Cell Homeostatic Proliferation Sclerotome Development RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Habenula Development Pallium Development Male Meiosis Chromosome Segregation Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Regulation Of Asymmetric Cell Division Oligodendrocyte Cell Fate Specification MRNA CDS Binding Meiotic Chromosome Separation Forebrain Dorsal/ventral Pattern Formation Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Cerebral Cortex Regionalization	Nucleoplasm Regulation Of MiRNA Transcription Positive Regulation Of Telomere Maintenance Protein Tag Activity Regulation Of Synaptic Vesicle Clustering Regulation Of DNA Strand Elongation Ino80 Complex Positive Regulation Of Telomere Maintenance In Response To DNA Damage Chromatin Organization Regulation Of MiRNA Metabolic Process
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