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MEX3B and RAP1GAP
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
MEX3B
RAP1GAP
Gene Name
mex-3 RNA binding family member B
RAP1 GTPase activating protein
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasmic MRNA Processing Body
Nucleoplasm
Cytoplasm
Golgi Membrane
Cytosol
Membrane
Molecular Function
Calcium Ion Binding
Zinc Ion Binding
Poly(A) RNA Binding
GTPase Activity
GTPase Activator Activity
Protein Binding
Ras GTPase Binding
Protein Homodimerization Activity
Rap GTPase Activator Activity
Biological Process
Protein Phosphorylation
Protein Autophosphorylation
Signal Transduction
Metabolic Process
Regulation Of Ras GTPase Activity
Positive Regulation Of Rap GTPase Activity
Negative Regulation Of Microvillus Assembly
Pathways
Rap1 signalling
Adaptive Immune System
Drugs
Diseases
GWAS
Liver enzyme levels (
18940312
)
Protein-Protein Interactions
6 interactors:
ATP13A2
NUDT3
RAP1GAP
SMAD4
SNUPN
UBE2D3
15 interactors:
BRAF
CDK1
CSNK1G2
DYNC1I1
GNAZ
MAP1LC3B
MAPK6
MEX3B
MLLT4
PFN2
PLK1
PRKACA
RALGDS
RAP1A
ZBTB12
Entrez ID
84206
5909
HPRD ID
15256
02609
Ensembl ID
ENSG00000183496
ENSG00000076864
Uniprot IDs
Q6ZN04
P47736
PDB IDs
1SRQ
3BRW
Enriched GO Terms of Interacting Partners
?
BMP Signaling Pathway
Diphosphoinositol Polyphosphate Catabolic Process
Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis
SnRNA Import Into Nucleus
Diadenosine Polyphosphate Catabolic Process
Negative Regulation Of Microvillus Assembly
RNA Import Into Nucleus
Nephrogenic Mesenchyme Morphogenesis
Transforming Growth Factor Beta Receptor Signaling Pathway
Nephrogenic Mesenchyme Development
Metanephric Mesenchyme Morphogenesis
Transcription Initiation From RNA Polymerase II Promoter
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Cellular Response To Manganese Ion
DNA-templated Transcription, Initiation
Regulation Of Microvillus Assembly
Endocardial Cell Differentiation
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Formation Of Anatomical Boundary
Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Endothelial Cell Activation
Response To Hypoxia
Regulation Of Transforming Growth Factor Beta2 Production
Positive Regulation Of SMAD Protein Import Into Nucleus
Atrioventricular Valve Formation
Sebaceous Gland Development
Somite Rostral/caudal Axis Specification
Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation
Brainstem Development
SMAD Protein Complex Assembly
Regulation Of SMAD Protein Import Into Nucleus
Atrioventricular Canal Development
Regulation Of Hair Follicle Development
Heart Valve Formation
Metanephric Mesenchyme Development
Endocardial Cushion Formation
Endocardium Development
Atrioventricular Valve Morphogenesis
Positive Regulation Of Rap GTPase Activity
Response To Manganese Ion
Regulation Of Hair Cycle
Endocardial Cushion Morphogenesis
Atrioventricular Valve Development
Regulation Of Rap GTPase Activity
Protein K11-linked Ubiquitination
Cardiac Epithelial To Mesenchymal Transition
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Regulation Of Rap Protein Signal Transduction
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Peptidyl-serine Phosphorylation
Regulation Of Synaptic Vesicle Exocytosis
Positive Regulation Of Catalytic Activity
Mitotic Nuclear Envelope Disassembly
Regulation Of Synaptic Vesicle Transport
Nuclear Envelope Disassembly
Positive Regulation Of Protein Phosphorylation
Protein Phosphorylation
Positive Regulation Of Phosphorylation
Regulation Of Neurotransmitter Secretion
Activation Of MAPKK Activity
Nuclear Envelope Organization
Positive Regulation Of Protein Modification Process
Positive Regulation Of Transferase Activity
Cellular Response To Growth Factor Stimulus
Activation Of Protein Kinase Activity
Response To Growth Factor
Regulation Of Protein Phosphorylation
Regulation Of Synaptic Transmission
Regulation Of Catalytic Activity
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Synaptic Vesicle Exocytosis
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Rap GTPase Activity
Positive Regulation Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
Nucleus Organization
Positive Regulation Of Protein Metabolic Process
Phosphorylation
Regulation Of Protein Kinase Activity
Intracellular Signal Transduction
Positive Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Neurotransmitter Secretion
Regulation Of Rap GTPase Activity
Regulation Of Phosphorylation
Regulation Of Cellular Amino Acid Metabolic Process
Regulation Of Kinase Activity
Negative Regulation Of Neurotransmitter Transport
Regulation Of Rap Protein Signal Transduction
Regulation Of Exocytosis
Positive Regulation Of MAPK Cascade
Fibroblast Growth Factor Receptor Signaling Pathway
Establishment Of Endothelial Barrier
Protein Localization To Chromosome
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Kinase Activity
Tagcloud
?
autophosphorylated
burst
c3g
crk
detrimental
fascin
filamentous
forced
gradual
gtpase
guanine
holds
hyperactivation
imperative
irrespective
labile
microspikes
motile
n17rap1
presumed
protrusions
recruits
releasing
reverses
sh3
unidentified
v12rap1
Tagcloud (Difference)
?
autophosphorylated
burst
c3g
crk
detrimental
fascin
filamentous
forced
gradual
gtpase
guanine
holds
hyperactivation
imperative
irrespective
labile
microspikes
motile
n17rap1
presumed
protrusions
recruits
releasing
reverses
sh3
unidentified
v12rap1
Tagcloud (Intersection)
?