EVA1A and TSPAN4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EVA1A	TSPAN4
Description		eva-1 homolog A, regulator of programmed cell death	tetraspanin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Plasma Membrane Membrane	Plasma Membrane Focal Adhesion Membrane Vesicle
	Molecular Function	Protein Binding	Antigen Binding Integrin Binding Protein Binding
	Biological Process	Cardiac Left Ventricle Morphogenesis Energy Reserve Metabolic Process Autophagy Apoptotic Process Heart Development Post-embryonic Development Lung Development TOR Signaling Connective Tissue Replacement	Protein-containing Complex Assembly
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Chronotype ( 30696823) Gout ( 32238385) Seborrheic dermatitis ( 29203360)	Falling risk ( 32999390)
Interacting Genes		8 interacting genes: GYPA MAP1LC3B MS4A13 MTNR1B PTN SAT1 SGTB TSPAN4	49 interacting genes: CATSPER1 CD46 CD81 CD9 CHRD CLDN11 CLEC2D CREB3 CREB5 CYSRT1 EVA1A FCHO1 FRS3 GNE GRN GUCD1 HOXA1 ITGA3 ITGA6 ITGB1 KRTAP10-1 KRTAP10-8 KRTAP4-11 KRTAP4-5 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE2B LCE2D LCE3A LCE3C LCE3D LCE4A LRRC25 LTB4R2 MDFI MGAT5B MKRN3 NBPF19 NOTCH2NLA NR4A3 OTX1 PHLDA1 PLSCR4 SGPL1 TEKT4 TMEM106A VGLL3
Entrez ID		84141	7106
HPRD ID		07827	04033
Ensembl ID		ENSG00000115363	ENSG00000214063
Uniprot IDs		Q9H8M9	A8MVV6 O14817
PDB IDs
Enriched GO Terms of Interacting Partners?			Keratinization Epidermis Development Keratin Filament Intermediate Filament Integrin Alpha6-beta1 Complex Integrin Alpha3-beta1 Complex Myoblast Fusion Involved In Skeletal Muscle Regeneration Myoblast Fusion Integrin Complex Cellular Response To Low-density Lipoprotein Particle Stimulus Cellular Response To Lipoprotein Particle Stimulus Cell-cell Fusion Syncytium Formation Syncytium Formation By Plasma Membrane Fusion Cerebellar Climbing Fiber To Purkinje Cell Synapse Identical Protein Binding CAMP Response Element Binding Regulation Of Cell Motility Hair Cycle Regulation Of Locomotion Integrin Binding Mesodermal Cell Differentiation Tissue Development
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