GLCE

Description		glucuronic acid epimerase
Image
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Calcium Ion Binding Isomerase Activity Racemase And Epimerase Activity, Acting On Carbohydrates And Derivatives Protein Homodimerization Activity Metal Ion Binding Heparosan-N-sulfate-glucuronate 5-epimerase Activity
	Biological Process	Positive Regulation Of Cell Population Proliferation Heparan Sulfate Proteoglycan Biosynthetic Process Heparin Proteoglycan Biosynthetic Process Negative Regulation Of Cell Projection Organization Positive Regulation Of SMAD Protein Signal Transduction
Pathways		HS-GAG biosynthesis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)
Novel Interacting Genes		1 novel interacting genes: NMB
Interacting Genes		11 interacting genes: BAG4 BCAR3 CASP8 ERBB2 ESR1 FBXO7 FGFR2 FGFR4 PAX2 PPM1D RB1CC1
Entrez ID		26035
HPRD ID		07020
Ensembl ID		ENSG00000138604
Uniprot IDs		O94923
PDB IDs		6HZZ 6I01 6I02
Enriched GO Terms of Interacting Partners?		Regulation Of Intracellular Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Regulation Of Cell Population Proliferation Negative Regulation Of Programmed Cell Death Positive Regulation Of Cell Population Proliferation Regulation Of Signal Transduction Positive Regulation Of Catalytic Activity Prostate Epithelial Cord Elongation Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Fibroblast Growth Factor Receptor Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Peptidyl-tyrosine Phosphorylation Positive Regulation Of MAPK Cascade Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Negative Regulation Of Apoptotic Process Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Prostate Gland Growth Regulation Of Catalytic Activity Branching Involved In Prostate Gland Morphogenesis Positive Regulation Of Signal Transduction Branch Elongation Of An Epithelium Regulation Of MAPK Cascade Stem Cell Differentiation Positive Regulation Of Metabolic Process Axis Elongation Regulation Of Metabolic Process Protein Tyrosine Kinase Activity Fibroblast Growth Factor Binding Prostate Gland Epithelium Morphogenesis Response To Lipid Morphogenesis Of A Branching Epithelium Morphogenesis Of Embryonic Epithelium Morphogenesis Of A Branching Structure Animal Organ Development Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Epithelial Tube Formation Receptor Complex Positive Regulation Of Epithelial Cell Proliferation Signal Transduction Cellular Response To Epidermal Growth Factor Stimulus Organ Growth Positive Regulation Of Macromolecule Biosynthetic Process Response To Epidermal Growth Factor Regulation Of Morphogenesis Of A Branching Structure Fibroblast Growth Factor Receptor Signaling Pathway Involved In Negative Regulation Of Apoptotic Process In Bone Marrow Cell Fibroblast Growth Factor Receptor Signaling Pathway Involved In Positive Regulation Of Cell Proliferation In Bone Marrow
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