ATL2 and ARL6

Number of citations of the paper that reports this interaction (PMID 10508919)
7

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATL2	ARL6
Gene Name		atlastin GTPase 2	ADP-ribosylation factor-like 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Cytoplasm Cytosol Axonemal Microtubule Plasma Membrane Cilium Axoneme Membrane Membrane Coat BBSome Ciliary Membrane Extracellular Vesicular Exosome Primary Cilium
	Molecular Function	GTPase Activity Protein Binding GTP Binding Identical Protein Binding	Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Golgi Organization Metabolic Process Protein Homooligomerization	Protein Targeting To Membrane Organelle Organization Small GTPase Mediated Signal Transduction Determination Of Left/right Symmetry Brain Development Visual Perception Regulation Of Smoothened Signaling Pathway Retina Layer Formation Wnt Signaling Pathway Melanosome Transport Cilium Assembly Fat Cell Differentiation Intermembrane Transport Protein Polymerization Protein Localization To Cilium
Pathways			Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
GWAS			Male infertility ( 19478329)
Protein-Protein Interactions		1 interactors: ARL6	6 interactors: ARL6IP1 ARL6IP4 ARL6IP5 ARL6IP6 ATL2 SEC61B
Entrez ID		64225	84100
HPRD ID		10662	10588
Ensembl ID		ENSG00000119787	ENSG00000113966
Uniprot IDs		Q8NHH9	Q9H0F7
PDB IDs			2H57
Enriched GO Terms of Interacting Partners?		Intermembrane Transport Protein Localization To Cilium Retina Layer Formation Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Neural Retina Development Retina Morphogenesis In Camera-type Eye Cellular Pigmentation Regulation Of Smoothened Signaling Pathway Protein Polymerization Determination Of Left/right Symmetry Determination Of Bilateral Symmetry Pigmentation Fat Cell Differentiation Camera-type Eye Morphogenesis Protein Targeting To Membrane Eye Morphogenesis Retina Development In Camera-type Eye Visual Perception Sensory Perception Of Light Stimulus Cilium Assembly Cilium Organization Establishment Of Vesicle Localization Vesicle Localization Cilium Morphogenesis Establishment Of Protein Localization To Membrane Wnt Signaling Pathway Cell Projection Assembly Establishment Of Organelle Localization Cellular Protein Complex Assembly Camera-type Eye Development Protein Localization To Membrane Eye Development Organelle Localization Protein Targeting Organelle Assembly Pattern Specification Process	Cotranslational Protein Targeting To Membrane Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Negative Regulation Of Mitochondrial Membrane Potential Retrograde Protein Transport, ER To Cytosol
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