TAGLN2 and EHD2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TAGLN2	EHD2
Gene Name		transgelin 2	EH-domain containing 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Vesicle Extracellular Vesicular Exosome	Nucleus Plasma Membrane Caveola Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Actin Filament Binding	Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding
	Biological Process	Epithelial Cell Differentiation	Endocytosis Blood Coagulation Metabolic Process Cortical Actin Cytoskeleton Organization Endocytic Recycling Protein Localization To Plasma Membrane Positive Regulation Of Myoblast Fusion Positive Regulation Of Endocytic Recycling
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: APP EHD2	13 interactors: AP1M1 AP1M2 AP2M1 BPGM DDX56 EHBP1 PICALM PICK1 RBSN SLC2A4 SPATA24 TAGLN2 TBC1D23
Entrez ID		8407	30846
HPRD ID		06864	10434
Ensembl ID		ENSG00000158710	ENSG00000024422
Uniprot IDs		P37802	Q9NZN4
PDB IDs		1WYM
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Blood Coagulation Hemostasis Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Regulation Of Body Fluid Levels Wound Healing Positive Regulation Of Endocytic Recycling Regulation Of Cardiac Muscle Cell Membrane Potential Neuron Remodeling Endocytosis Regulation Of Endocytic Recycling Response To Wounding Positive Regulation Of Myoblast Fusion Cellular Copper Ion Homeostasis Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Regulation Of Myoblast Fusion Endocytic Recycling Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Cortical Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Positive Regulation Of Myotube Differentiation Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Targeting To Plasma Membrane Ionotropic Glutamate Receptor Signaling Pathway Vesicle-mediated Transport Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Intracellular Transport Axon Cargo Transport Mating Neuromuscular Junction Development Regulation Of Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Phase Transition Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Regulation Of Myotube Differentiation Regulation Of Protein Tyrosine Kinase Activity	Regulation Of Defense Response To Virus By Virus Membrane Organization Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Cell Differentiation Clathrin-mediated Endocytosis Antigen Processing And Presentation Of Peptide Antigen Golgi Vesicle Transport Vesicle-mediated Transport Antigen Processing And Presentation Intracellular Transport Amylopectin Biosynthetic Process Positive Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Intracellular Protein Transport Developmental Process Post-Golgi Vesicle-mediated Transport Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Establishment Of Localization In Cell Viral Process Immune System Process Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Negative Regulation Of Metalloendopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Synaptic Transmission Cellular Protein Localization Cargo Loading Into Vesicle Protein Transport Cellular Localization Iron Ion Import Into Cell Establishment Of Protein Localization Regulation Of Endocytosis DNA Methylation Involved In Embryo Development Establishment Of Vesicle Localization Vesicle Organization Pigment Granule Maturation Endosome To Melanosome Transport Glucose Import Endosomal Transport Vesicle Localization Dendritic Spine Maintenance Cellular Pigment Accumulation Synaptic Vesicle Maturation Positive Regulation Of Beta-amyloid Formation Neuronal Ion Channel Clustering Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Iron Ion Import Negative Regulation Of Actin Nucleation
Tagcloud ?		a10 adenocarcinoma barrett biologically cox7a2 details differentially entitled fresh frozen goal histologically issue lymph maldi node precursor predicting premalignant proteomic proteomics regional revealing s100 special underscore validating validation z	acted adapter converts cytoplasm cytoskeleton deprived deregulated direction e2 enrichment fhl2 homer3 hydroxytamoxifen mcf modulator oestrogen oht organelle overlap pf rationale remarkable remodelling reorganisation reprogrammed rhof transcriptome uncovered unexpectedly
Tagcloud (Difference) ?		a10 adenocarcinoma barrett biologically cox7a2 details differentially entitled fresh frozen goal histologically issue lymph maldi node precursor predicting premalignant proteomic proteomics regional revealing s100 special underscore validating validation z	acted adapter converts cytoplasm cytoskeleton deprived deregulated direction e2 enrichment fhl2 homer3 hydroxytamoxifen mcf modulator oestrogen oht organelle overlap pf rationale remarkable remodelling reorganisation reprogrammed rhof transcriptome uncovered unexpectedly
Tagcloud (Intersection) ?