MIRLET7G and PTCD3

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIRLET7G	PTCD3
Description		microRNA let-7g	pentatricopeptide repeat domain 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Small Ribosomal Subunit Cytosol Ribosome Plasma Membrane Ribonucleoprotein Complex
	Molecular Function	MRNA Base-pairing Post-transcriptional Repressor Activity	RNA Binding Protein Binding RRNA Binding Ribosomal Small Subunit Binding
	Biological Process	Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MiRNA-mediated Post-transcriptional Gene Silencing Positive Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Negative Regulation Of SMAD Protein Signal Transduction Cellular Response To Glucose Stimulus Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell	Regulation Of Translation Mitochondrial Translation
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 23974872)	Diastolic blood pressure ( 27841878) Facial emotion recognition (sad faces) ( 28608620) Pulse pressure ( 27841878) Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132) Systolic blood pressure ( 27841878)
Interacting Genes		116 interacting genes: ADARB1 APOBEC3B AQR ATXN2L C1QBP CCAR1 CDC40 CDC5L CELF1 CHERP CPSF1 CRTAP CSTF3 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 EPRS1 ESRP1 FAM98A FAM98B FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PAXBP1 PDCD11 PLOD1 PLRG1 PTBP1 PTCD3 PUF60 PUM1 PUM2 PURA PURB QARS1 RARS1 RBFOX2 RBM10 RBM12B RBM14 RBM17 RBM4 RBM4B RBM5 RBM6 RBMS1 RTCA RTCB SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SF3B5 SFPQ SPOUT1 STRBP SUGP1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 XAB2 YBX1 YBX2 YBX3 ZFR	22 interacting genes: ATF4 BIRC7 HGS IFITM2 LNX2 LUC7L2 MIR128-2 MIR18B MIR200B MIR200C MIR205 MIR21 MIR214 MIR34B MIR34C MIR363 MIRLET7A2 MIRLET7F2 MIRLET7G MT-RNR1 TBPL1 UBE3A
Entrez ID		406890	55037
HPRD ID			08631
Ensembl ID		ENSG00000199150	ENSG00000132300
Uniprot IDs			Q96EY7
PDB IDs			3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSP 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2
Enriched GO Terms of Interacting Partners?		RNA Binding RNA Processing Nucleic Acid Binding RNA Metabolic Process MRNA Processing MRNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Complex Macromolecule Metabolic Process Regulation Of RNA Splicing Nucleoplasm Regulation Of MRNA Metabolic Process Nucleus Catalytic Step 2 Spliceosome Post-transcriptional Regulation Of Gene Expression Ribonucleoprotein Complex MiRNA Binding Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule Regulation Of Translation MRNA 3'-UTR Binding Aminoacyl-tRNA Synthetase Multienzyme Complex Regulation Of RNA Stability Regulation Of Gene Expression Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Spliceosomal Complex Assembly Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Catabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of MRNA Catabolic Process U2 SnRNP RNA Stabilization MRNA Stabilization Negative Regulation Of Translation Regulation Of Metabolic Process MiRNA Processing Protein-RNA Complex Assembly TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity U2-type Prespliceosome Assembly Negative Regulation Of Macromolecule Metabolic Process	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing RISC Complex Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Vasculature Development Negative Regulation Of Angiogenesis Regulation Of Angiogenesis Regulation Of Vasculature Development MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Translation Positive Regulation Of Cardiac Muscle Hypertrophy MiRNA-mediated Gene Silencing By MRNA Destabilization Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Connective Tissue Replacement Regulation Of Multicellular Organismal Development Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Connective Tissue Replacement Regulation Of Osteoblast Differentiation Negative Regulation Of Interleukin-33 Production Negative Regulation Of Endothelial Cell Migration Regulation Of Cardiac Muscle Hypertrophy Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Tissue Remodeling Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Metabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of Anatomical Structure Morphogenesis MRNA Destabilization RNA Destabilization Regulation Of Translation Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Developmental Process Regulation Of Muscle System Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Protein Metabolic Process
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