FZD9 and WNT7A

Number of citations of the paper that reports this interaction (PMID 15705594)
34

Data Source:
HPRD (in vivo)

		FZD9	WNT7A
Gene Name		frizzled class receptor 9	wingless-type MMTV integration site family, member 7A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane Filopodium Membrane Perinuclear Region Of Cytoplasm	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Endoplasmic Reticulum Lumen Golgi Lumen Plasma Membrane Cell Surface
	Molecular Function	G-protein Coupled Receptor Activity Wnt-protein Binding Protein Homodimerization Activity Wnt-activated Receptor Activity Protein Heterodimerization Activity	Receptor Binding Frizzled Binding Cytokine Activity Receptor Agonist Activity
	Biological Process	G-protein Coupled Receptor Signaling Pathway Nervous System Development Neuroblast Proliferation Learning Or Memory B Cell Differentiation Non-canonical Wnt Signaling Pathway Canonical Wnt Signaling Pathway	Embryonic Axis Specification Cartilage Condensation Angiogenesis Chondrocyte Differentiation Neurotransmitter Secretion Sex Differentiation Asymmetric Protein Localization Dorsal/ventral Pattern Formation Positive Regulation Of Endothelial Cell Migration Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Cerebellar Granule Cell Differentiation Cell Proliferation In Forebrain Central Nervous System Vasculogenesis Establishment Of Cell Polarity Neuron Differentiation Regulation Of Axon Diameter Response To Estradiol Somatic Stem Cell Maintenance Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Non-canonical Wnt Signaling Pathway Wnt Signaling Pathway Involved In Wound Healing, Spreading Of Epidermal Cells Embryonic Digit Morphogenesis Negative Regulation Of Apoptotic Process Cell Fate Commitment Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of JNK Cascade Somatic Stem Cell Division Stem Cell Development Negative Regulation Of Neurogenesis Synapse Organization Positive Regulation Of Synapse Assembly Palate Development Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Oviduct Development Canonical Wnt Signaling Pathway Uterus Morphogenesis Lens Fiber Cell Development Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Metabolic disorders of biological oxidation enzymes GPCR ligand binding Class B/2 (Secretin family receptors)	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 Signaling by Wnt Signaling by WNT in cancer Metabolic disorders of biological oxidation enzymes GPCR ligand binding WNT ligand biogenesis and trafficking Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease-related biomarkers ( 23144326)
Protein-Protein Interactions		6 interactors: KRTAP10-3 MDFI SIAH1 WNT1 WNT2 WNT7A	3 interactors: FZD5 FZD9 STRN4
Entrez ID		8326	7476
HPRD ID		03460	03341
Ensembl ID		ENSG00000188763
Uniprot IDs		O00144	O00755
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Receptor Activity Regulation Of Wnt Signaling Pathway Positive Regulation Of Signal Transduction Canonical Wnt Signaling Pathway Axis Specification Regulation Of Receptor Activity Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Anatomical Structure Morphogenesis Wnt Signaling Pathway Organ Morphogenesis Positive Regulation Of Embryonic Development Cell Fate Commitment Regulation Of Signal Transduction Neuron Differentiation Embryo Development Single Organism Reproductive Process Regulation Of Signaling Cerebellum Morphogenesis Developmental Induction Reproductive Process Embryonic Axis Specification Hindbrain Morphogenesis Cell Differentiation Positive Regulation Of Fibroblast Proliferation Pattern Specification Process Embryonic Organ Development Reproductive Structure Development Generation Of Neurons Reproductive System Development Neurogenesis Skeletal System Development Embryonic Pattern Specification Sensory Organ Development Lens Development In Camera-type Eye Regulation Of Fibroblast Proliferation Regulation Of Transcription From RNA Polymerase II Promoter System Development Embryonic Morphogenesis Tissue Morphogenesis Midbrain-hindbrain Boundary Maturation During Brain Development Cerebellum Formation Wnt Signaling Pathway Involved In Wound Healing, Spreading Of Epidermal Cells Embryonic Placenta Development Cerebellum Development Regulation Of Embryonic Development Dorsal/ventral Pattern Formation Positive Regulation Of JNK Cascade Tube Development	Non-canonical Wnt Signaling Pathway Canonical Wnt Signaling Pathway Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Lymphocyte Differentiation Regulation Of Chorionic Trophoblast Cell Proliferation Spemann Organizer Formation Wnt Signaling Pathway Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Leukocyte Differentiation Lymphocyte Activation Chorionic Trophoblast Cell Differentiation Chorion Development Regulation Of Tight Junction Assembly Leukocyte Activation Post-embryonic Camera-type Eye Development Branching Involved In Labyrinthine Layer Morphogenesis Hemopoiesis Anterior/posterior Axis Specification, Embryo Cell Activation Immune System Development Labyrinthine Layer Morphogenesis Apoptotic Process Involved In Morphogenesis Dorsal/ventral Axis Specification Labyrinthine Layer Blood Vessel Development Apoptotic Process Involved In Development Embryonic Placenta Morphogenesis Cell Differentiation Involved In Embryonic Placenta Development Placenta Blood Vessel Development Developmental Programmed Cell Death Developmental Induction Positive Regulation Of Interferon-gamma Production Embryonic Axis Specification G-protein Coupled Receptor Signaling Pathway Neuroblast Proliferation Labyrinthine Layer Development Embryonic Camera-type Eye Development Regulation Of Cell Junction Assembly T Cell Differentiation In Thymus Anterior/posterior Axis Specification Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity Regulation Of Interferon-gamma Production Stem Cell Proliferation Embryonic Pattern Specification Generation Of Neurons
Tagcloud ?		ascl2 c4b dab2ip dlk1 eya4 fabp3 gas7 hdac9 hoxa11 hoxa5 hoxa9 hoxb13 ihh ipf1 isl1 mest mme pax6 ptgs2 rassf1 rbp1 scgb3a1 sept5 serpina5 sox1 sox17 tbx1 tff1 thy1	abcb1b administrated brosis colla1 corroborated dkk1 dkk2 dkk3 dkk4 fi frizzled frzb fz1 fz5 fz7 nano nephrotoxicity osteopontin sfrp tio2 wnt1 wnt10a wnt11 wnt2 wnt3 wnt4 wnt5a wnt6 wnt9a
Tagcloud (Difference) ?		ascl2 c4b dab2ip dlk1 eya4 fabp3 gas7 hdac9 hoxa11 hoxa5 hoxa9 hoxb13 ihh ipf1 isl1 mest mme pax6 ptgs2 rassf1 rbp1 scgb3a1 sept5 serpina5 sox1 sox17 tbx1 tff1 thy1	abcb1b administrated brosis colla1 corroborated dkk1 dkk2 dkk3 dkk4 fi frizzled frzb fz1 fz5 fz7 nano nephrotoxicity osteopontin sfrp tio2 wnt1 wnt10a wnt11 wnt2 wnt3 wnt4 wnt5a wnt6 wnt9a
Tagcloud (Intersection) ?