KHDC4 and RBM39

Number of citations of the paper that reports this interaction (PubMedID 26871637)
43

Data Source:
BioGRID (two hybrid)

		KHDC4	RBM39
Description		KH domain containing 4, pre-mRNA splicing factor	RNA binding motif protein 39
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm	Nucleus Nucleoplasm Microtubule Cytoskeleton Nuclear Speck Protein-containing Complex Centriolar Satellite
	Molecular Function	RNA Binding Protein Binding	Nucleic Acid Binding RNA Binding Protein Binding RS Domain Binding U1 SnRNP Binding
	Biological Process	MRNA Splice Site Recognition MRNA Processing RNA Splicing	RNA Processing MRNA Processing RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		21 interacting genes: BANP C14orf119 DNAJC5 KCNIP3 MAGEA12 NRF1 NUTF2 PIDD1 PRKAB2 PRR13 PSMB1 PUF60 QRICH1 RBM23 RBM39 RHOXF2 SAT1 SPANXN2 U2AF2 ZDHHC17 ZRSR2	56 interacting genes: AK8 APP ARL6IP4 ASH2L BANP CEBPA CHERP CLK2 CSNK2A1 DARS1-AS1 DCAF15 DDX39B DVL3 ESR1 ESR2 FAM200A GOLGA2 HOMEZ INO80B JUN KHDC4 KMT2A KRTAP12-2 MCPH1 MLX MTNR1A NCOA6 NKAP NKAPD1 OGT PGR PHC2 POU6F2 PRPF38A PRPF40A RBBP5 RBM23 RBM25 REL RNF113A RP9P SAP30BP SDCBP SF3B4 SP100 SREK1 SREK1IP1 SRRM4 THAP1 TOE1 TTC14 U2AF2 USP7 WDR5 ZBTB22 ZCCHC10
Entrez ID		22889	9584
HPRD ID		17198	09201
Ensembl ID		ENSG00000132680	ENSG00000131051
Uniprot IDs		Q7Z7F0	A0A384NQ03 B4DRA0 Q14498
PDB IDs		2YQR	2JRS 2MHN 4OO6 4OZ0 4OZ1 4YUD 6PAI 6Q0R 6Q0V 6Q0W 6SJ7 6UD7 6UE5 7Q33
Enriched GO Terms of Interacting Partners?		Pre-mRNA 3'-splice Site Binding U2AF Complex Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome U1 SnRNP Binding RNA Splicing Regulation Of RNA Splicing MRNA Processing Nucleus Nucleic Acid Binding Regulation Of MRNA Metabolic Process MRNA Metabolic Process Spermidine Binding Perforant Pathway To Dendrate Granule Cell Synapse Spermidine Acetylation Putrescine Catabolic Process MRNA Splicing, Via Spliceosome Spliceosomal Complex Assembly Protein-RNA Complex Assembly RNA Splicing, Via Transesterification Reactions Poly-pyrimidine Tract Binding Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Nucleoplasm RNA Processing Diamine N-acetyltransferase Activity Protein Localization To Nuclear Pore Endopeptidase Complex Identical Protein Binding	Nucleoplasm RNA Splicing MRNA Processing MRNA Metabolic Process MLL1/2 Complex Regulation Of RNA Metabolic Process Histone Methyltransferase Complex Nucleus RNA Metabolic Process MLL3/4 Complex RNA Processing Nucleic Acid Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression, Epigenetic Nuclear Speck Nucleobase-containing Compound Metabolic Process Nucleic Acid Binding Spliceosomal Complex MLL1 Complex Regulation Of Transcription By RNA Polymerase II Estrogen Response Element Binding Regulation Of Primary Metabolic Process Identical Protein Binding Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Set1C/COMPASS Complex Negative Regulation Of Biosynthetic Process Rhythmic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Initiation-coupled Chromatin Remodeling Regulation Of Gluconeogenesis Negative Regulation Of RNA Metabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Nuclear Steroid Receptor Activity MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nuclear Estrogen Receptor Activity RNA Splicing, Via Transesterification Reactions Regulation Of Metabolic Process RNA Binding Negative Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process
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