SYMPK and SSU72

Number of citations of the paper that reports this interaction (PMID 20861839)
34

Data Source:
BioGRID (x-ray crystallography, pull down)

		SYMPK	SSU72
Gene Name		symplekin	SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Tight Junction	Nucleus Cytoplasm
	Molecular Function	Protein Binding	Protein Binding CTD Phosphatase Activity
	Biological Process	MRNA Polyadenylation Cell Adhesion Positive Regulation Of Protein Dephosphorylation	MRNA Polyadenylation Dephosphorylation Of RNA Polymerase II C-terminal Domain
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CSTF2 HSF1 HTT SSU72 SUMO1 TOP1	5 interactors: MAPK8 MAPK9 RAD21 STAG2 SYMPK
Entrez ID		8189	29101
HPRD ID		09090	13712
Ensembl ID		ENSG00000125755	ENSG00000160075
Uniprot IDs		Q92797	Q9NP77
PDB IDs		3O2Q 3O2S 3O2T 3ODR 3ODS 4H3H 4H3K	3O2Q 3O2S 4H3H 4H3K
Enriched GO Terms of Interacting Partners?		MRNA Polyadenylation RNA Polyadenylation Heterocycle Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA 3'-end Processing Neural Plate Formation RNA 3'-end Processing Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Regulation Of Protein Phosphatase Type 2A Activity Protein Localization To Nucleus Circadian Rhythm PML Body Organization Quinolinate Biosynthetic Process Dephosphorylation Of RNA Polymerase II C-terminal Domain Negative Regulation Of Synaptic Transmission, Dopaminergic Lactate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Protein Localization To Nuclear Pore Paraxial Mesoderm Formation Quinolinate Metabolic Process Protein Localization To Nuclear Envelope Cellular Response To CGMP Cellular Aromatic Compound Metabolic Process Response To CGMP Serotonin Transport Regulation Of Gene Expression Embryo Development Sperm Ejaculation Neural Plate Morphogenesis L-glutamate Import Regulation Of Developmental Growth Rhythmic Process Citrulline Metabolic Process Embryonic Process Involved In Female Pregnancy Lactate Metabolic Process Urea Cycle Embryonic Cleavage Neurotransmitter Uptake Urea Metabolic Process Organelle Organization Thalamus Development Striatum Development Paraxial Mesoderm Morphogenesis Neural Plate Development Amino Acid Import	JUN Phosphorylation Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Response To Cadmium Ion Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway JNK Cascade Regulation Of Circadian Rhythm Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Response To UV Activation Of Innate Immune Response Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Positive Regulation Of Innate Immune Response Apoptotic Process Positive Regulation Of Apoptotic Signaling Pathway Programmed Cell Death Meiotic Cell Cycle Cell Death Response To Mechanical Stimulus Death MAPK Cascade Fc-epsilon Receptor Signaling Pathway Chromosome Segregation Negative Regulation Of DNA Endoreduplication Regulation Of Innate Immune Response Positive Regulation Of Deacetylase Activity Positive Regulation Of Prostaglandin Biosynthetic Process Fc Receptor Signaling Pathway Signal Transduction By Phosphorylation Positive Regulation Of Determination Of Dorsal Identity Response To Lipopolysaccharide Mitotic Nuclear Division Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Metal Ion Response To Molecule Of Bacterial Origin Response To Light Stimulus Apoptotic Signaling Pathway Regulation Of DNA Endoreduplication
Tagcloud ?			alleles choose cleavage conversely degrades disrupt elongation exonuclease exosome generates keeps localize nrd1 nucleolar options pcf11 poly polyadenylated polyadenylation rat1 rnas sen1 snorna snornas termination transcribed transcribing trimming xrn2
Tagcloud (Difference) ?			alleles choose cleavage conversely degrades disrupt elongation exonuclease exosome generates keeps localize nrd1 nucleolar options pcf11 poly polyadenylated polyadenylation rat1 rnas sen1 snorna snornas termination transcribed transcribing trimming xrn2
Tagcloud (Intersection) ?