AKAP1 and AMY1A

Number of citations of the paper that reports this interaction (PubMedID 12414807)
0

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		AKAP1	AMY1A
Description		A-kinase anchoring protein 1	amylase alpha 1A
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane	Extracellular Region Extracellular Space Extracellular Exosome
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Protein Kinase A Regulatory Subunit Binding	Catalytic Activity Alpha-amylase Activity Calcium Ion Binding Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds Chloride Ion Binding Cation Binding Metal Ion Binding
	Biological Process	Apoptotic Process Antiviral Innate Immune Response	Carbohydrate Metabolic Process Oligosaccharide Metabolic Process
Pathways		Mitochondrial calcium ion transport Factors involved in megakaryocyte development and platelet production	Digestion of dietary carbohydrate Digestion of dietary carbohydrate Digestion of dietary carbohydrate
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Crohn's disease ( 26192919) Freckles ( 29895819) Inflammatory bowel disease ( 26192919) Male-pattern baldness ( 27182965)	Blood protein levels ( 30072576)
Interacting Genes		12 interacting genes: AMY1A CAV1 CFAP91 DYSF MYCBP PPP1CA PRKAR1A PRKAR1B PRKAR2A PRKAR2B PTPN21 RNF10	3 interacting genes: AKAP1 AKAP8 MUC7
Entrez ID		8165	276
HPRD ID		03905	00096
Ensembl ID		ENSG00000121057	ENSG00000237763
Uniprot IDs		A0A140VK05 B4DN86 Q92667	P0DTE7 P0DTE8 P0DUB6 Q6NSB3
PDB IDs			1C8Q 1JXJ 1JXK 1MFU 1MFV 1NM9 1Q4N 1SMD 1XV8 1Z32 3BLK 3BLP 3DHP
Enriched GO Terms of Interacting Partners?		CAMP-dependent Protein Kinase Complex CAMP-dependent Protein Kinase Regulator Activity CAMP-dependent Protein Kinase Inhibitor Activity Ciliary Base Protein Kinase A Catalytic Subunit Binding CAMP Binding Negative Regulation Of CAMP/PKA Signal Transduction Regulation Of CAMP/PKA Signal Transduction Nucleotide-activated Protein Kinase Complex Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Glutamatergic Synapse Axoneme Plasma Membrane Raft Negative Regulation Of Intracellular Signal Transduction G Protein-coupled Receptor Signaling Pathway Protein Domain Specific Binding Postsynapse Cellular Response To Glucagon Stimulus Ubiquitin Protein Ligase Binding Response To Glucagon Cellular Response To Peptide Hormone Stimulus Negative Regulation Of Signal Transduction Modulation Of Chemical Synaptic Transmission Negative Regulation Of Signaling Negative Regulation Of Cell Communication Mesoderm Formation Multivesicular Body Regulation Of Vesicle-mediated Transport Positive Regulation Of Glucose Metabolic Process Regulation Of System Process Inward Rectifier Potassium Channel Inhibitor Activity Monocyte Activation Involved In Immune Response Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Formation Of Primary Germ Layer Regulation Of Carbohydrate Catabolic Process Centrosome Negative Regulation Of Endocytosis Alpha-amylase Activity Caveolar Macromolecular Signaling Complex Regulation Of Cell Communication Response To Peptide Hormone Regulation Of Signaling Regulation Of Endocytosis RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Response To Antipsychotic Drug Radial Spoke Stalk Neuromuscular Junction Regulation Of Cardiac Muscle Contraction Regulation Of Small Molecule Metabolic Process	Protein Kinase A Regulatory Subunit Binding Defense Response To Other Organism Defense Response To Symbiont Defense Response Response To Other Organism Immune Response Response To External Biotic Stimulus Immune System Process Female Pronucleus Mitotic Chromosome Condensation Cellular Response To Prostaglandin E Stimulus Innate Immune Response Cellular Response To Prostaglandin Stimulus Response To Prostaglandin E Response To Stress Condensed Chromosome NF-kappaB Binding Chromosome Condensation
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