AMY1A and AKAP1

Number of citations of the paper that reports this interaction (PMID 12414807)
6

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		AMY1A	AKAP1
Gene Name		amylase, alpha 1A (salivary)	A kinase (PRKA) anchor protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Extracellular Vesicular Exosome	Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane Integral Component Of Membrane
	Molecular Function	Alpha-amylase Activity Protein Binding Metal Ion Binding	RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Carbohydrate Metabolic Process Digestion	Blood Coagulation
Pathways		Myoclonic epilepsy of Lafora Digestion of dietary carbohydrate Glycogen storage diseases Metabolism of carbohydrates	Factors involved in megakaryocyte development and platelet production
Drugs		Beta-D-Glucose Pyroglutamic Acid 5-Hydroxymethyl-Chonduritol 4,6-Dideoxy-4-Amino-Alpha-D-Glucose Tris(Hydroxyethyl)Aminomethane
Diseases
GWAS
Protein-Protein Interactions		3 interactors: AKAP1 AKAP8 MUC7	11 interactors: AMY1A APP CAV1 MAATS1 MYCBP PPP1CA PRKAR1A PRKAR1B PRKAR2A PRKAR2B PTPN21
Entrez ID		276	8165
HPRD ID		00096	03905
Ensembl ID		ENSG00000237763	ENSG00000121057
Uniprot IDs		P04745 Q6NSB3	B4DN86 Q92667
PDB IDs		1C8Q 1JXJ 1JXK 1MFU 1MFV 1NM9 1Q4N 1SMD 1XV8 1Z32 3BLK 3BLP 3DHP
Enriched GO Terms of Interacting Partners?			Negative Regulation Of CAMP-dependent Protein Kinase Activity Regulation Of CAMP-dependent Protein Kinase Activity Activation Of Protein Kinase A Activity Renal Water Homeostasis Cellular Response To Glucagon Stimulus Negative Regulation Of Protein Serine/threonine Kinase Activity Energy Reserve Metabolic Process Water Transport Fluid Transport Multicellular Organismal Water Homeostasis Activation Of Phospholipase C Activity Response To Glucagon Positive Regulation Of Phospholipase C Activity Blood Coagulation Hemostasis Water Homeostasis Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Regulation Of Body Fluid Levels Wound Healing Renal System Process Negative Regulation Of Transferase Activity Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Protein Phosphorylation Response To Wounding Regulation Of Protein Kinase Activity Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Negative Regulation Of Phosphorylation Negative Regulation Of Cellular Protein Metabolic Process Generation Of Precursor Metabolites And Energy Chemical Homeostasis Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Negative Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Insulin Secretion Positive Regulation Of Hydrolase Activity Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Phosphorylation Regulation Of Peptide Hormone Secretion Neurotrophin Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Cellular Response To Growth Factor Stimulus
Tagcloud ?			2a akaps bad barbier biol chaturvedi competes contributed dephosphorylates depletion dissociation exist p90 patel phosphatases pka pkarialpha poppleton pp2ac redistribution rsk rsk1 rsk2 rsk3 silenced silencing stringfield subcellular unstimulated
Tagcloud (Difference) ?			2a akaps bad barbier biol chaturvedi competes contributed dephosphorylates depletion dissociation exist p90 patel phosphatases pka pkarialpha poppleton pp2ac redistribution rsk rsk1 rsk2 rsk3 silenced silencing stringfield subcellular unstimulated
Tagcloud (Intersection) ?