AMY1A and AKAP8

Number of citations of the paper that reports this interaction (PMID 12414807)
6

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo, in vitro)

		AMY1A	AKAP8
Gene Name		amylase, alpha 1A (salivary)	A kinase (PRKA) anchor protein 8
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Extracellular Vesicular Exosome	Condensed Chromosome Female Pronucleus Nucleus Nucleoplasm Mitochondrion Golgi Apparatus Membrane Nuclear Matrix
	Molecular Function	Alpha-amylase Activity Protein Binding Metal Ion Binding	Double-stranded DNA Binding Zinc Ion Binding Protein Kinase A Regulatory Subunit Binding Poly(A) RNA Binding
	Biological Process	Carbohydrate Metabolic Process Digestion	Mitotic Nuclear Division Mitotic Chromosome Condensation Signal Transduction
Pathways		Myoclonic epilepsy of Lafora Digestion of dietary carbohydrate Glycogen storage diseases Metabolism of carbohydrates
Drugs		Beta-D-Glucose Pyroglutamic Acid 5-Hydroxymethyl-Chonduritol 4,6-Dideoxy-4-Amino-Alpha-D-Glucose Tris(Hydroxyethyl)Aminomethane
Diseases
GWAS
Protein-Protein Interactions		3 interactors: AKAP1 AKAP8 MUC7	10 interactors: AMY1A CASP3 CCND1 CCND2 CCND3 CSNK2A1 DDX5 MCM2 PRKAR2A RELA
Entrez ID		276	10270
HPRD ID		00096	05258
Ensembl ID		ENSG00000237763	ENSG00000105127
Uniprot IDs		P04745 Q6NSB3	M0QYL4 O43823
PDB IDs		1C8Q 1JXJ 1JXK 1MFU 1MFV 1NM9 1Q4N 1SMD 1XV8 1Z32 3BLK 3BLP 3DHP
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Metabolic Process Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Response To UV Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transferase Activity Cellular Response To Growth Factor Stimulus Negative Regulation Of Cellular Metabolic Process Response To Growth Factor Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cell Cycle Regulation Of Catalytic Activity Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Cycle Positive Regulation Of Catalytic Activity Regulation Of Metabolic Process Positive Regulation Of Phosphorylation Response To Light Stimulus Negative Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Acetaldehyde Metabolic Process Cellular Response To Organic Substance Cell Division Response To Radiation Negative Regulation Of Cell Cycle Positive Regulation Of Schwann Cell Differentiation Response To Vitamin Cellular Response To Stimulus Negative Regulation Of Protein Catabolic Process Response To Drug Re-entry Into Mitotic Cell Cycle Regulation Of Schwann Cell Differentiation Response To Tumor Necrosis Factor Negative Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction Response To Cobalamin
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