PREPL

Description		prolyl endopeptidase like
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Golgi Apparatus Trans-Golgi Network Cytosol Cytoskeleton
	Molecular Function	Serine-type Endopeptidase Activity Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Regulation Of Synaptic Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS		antipsychotic drug dosage in schizophrenia or schizoaffective disorder ( 26821981) Ceramide levels (C24:0) ( 32489964) Daytime nap ( 33568662) Femur bone mineral density x serum urate levels interaction ( 34046847) Refractive error ( 32231278)
Interacting Genes		3 interacting genes: CAPN3 COIL RIPK4
Entrez ID		9581
HPRD ID		17189
Ensembl ID		ENSG00000138078
Uniprot IDs		Q4J6C6
PDB IDs		7OBM 8RFB
Enriched GO Terms of Interacting Partners?		Calcium-dependent Self Proteolysis Ligase Regulator Activity Positive Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Negative Regulation Of Protein Sumoylation Self Proteolysis Regulation Of Skeletal Muscle Tissue Regeneration Cellular Response To Salt Stress Positive Regulation Of Skeletal Muscle Tissue Regeneration Sodium Ion Binding G1 To G0 Transition Involved In Cell Differentiation U1 SnRNA Binding U2 SnRNA Binding Calcium-dependent Cysteine-type Endopeptidase Activity Titin Binding G1 To G0 Transition Response To Salt Stress Regulation Of Protein Sumoylation
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