CAMK2B and RPL11

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CAMK2B	RPL11
Gene Name		calcium/calmodulin-dependent protein kinase II beta	ribosomal protein L11
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Microtubule Organizing Center Cytosol Plasma Membrane Endocytic Vesicle Membrane Sarcoplasmic Reticulum Membrane Spindle Midzone	Nucleolus Cytosol Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Calmodulin-dependent Protein Kinase Activity Calmodulin Binding ATP Binding Protein Homodimerization Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding Poly(A) RNA Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Inhibitory G-protein Coupled Receptor Phosphorylation Protein Phosphorylation Calcium Ion Transport Signal Transduction Synaptic Transmission Positive Regulation Of Neuron Projection Development Regulation Of Skeletal Muscle Adaptation Peptidyl-serine Phosphorylation Cytokine-mediated Signaling Pathway Regulation Of Synaptic Transmission, Cholinergic Cellular Response To Heat Response To Cadmium Ion Protein Autophosphorylation Regulation Of Long-term Neuronal Synaptic Plasticity Neuromuscular Process Controlling Balance Regulation Of Synapse Structural Plasticity Regulation Of Calcium Ion Transport Interferon-gamma-mediated Signaling Pathway Activation Of Meiosis Involved In Egg Activation Regulation Of Dendritic Spine Development Positive Regulation Of Dendritic Spine Morphogenesis Positive Regulation Of Synapse Maturation Regulation Of Cellular Response To Heat Positive Regulation Of Apoptotic Signaling Pathway	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation Translational Elongation Translational Termination Protein Targeting SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Protein Localization To Nucleus Ribosomal Large Subunit Biogenesis Cellular Protein Metabolic Process
Pathways		Interferon Signaling Cytokine Signaling in Immune system Cellular response to heat stress CREB phosphorylation through the activation of Ras Trafficking of AMPA receptors Interferon gamma signaling HSF1-dependent transactivation Activation of NMDA receptor upon glutamate binding and postsynaptic events CREB phosphorylation through the activation of CaMKII Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Unblocking of NMDA receptor, glutamate binding and activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ras activation uopn Ca2+ infux through NMDA receptor Post NMDA receptor activation events Transmission across Chemical Synapses	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Metabolic syndrome ( 22399527)
Protein-Protein Interactions		37 interactors: ACOT7 ACTN4 AP5B1 ATXN1 CAMK2D CAMK2N2 CCM2L COL4A3 ETS1 FAM171A2 GAPDH GRIN2A GRIN2B ITPKA KRTAP10-11 KRTAP19-5 KRTAP19-7 MAD2L2 MED18 MGAT5B MORF4L1 MRPL11 MVP PHKB PLCB3 POP5 RAP2B RBFOX2 RBPMS RPL11 RXRG SEMA4G SMYD3 SPRYD7 THRB TTC5 YWHAB	14 interactors: ARFGAP1 BLMH C12orf5 CAMK2B HP IGF1R KRT40 KRTAP10-7 LIG4 MDM2 NEDD8 PAIP2 PML STAT3
Entrez ID		816	6135
HPRD ID		12127	10364
Ensembl ID		ENSG00000058404	ENSG00000142676
Uniprot IDs		A4D2J9 Q13554	P62913 Q5VVD0
PDB IDs		3BHH	3J3B
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Excitatory Postsynaptic Membrane Potential Intracellular Receptor Signaling Pathway Cellular Response To Stimulus Regulation Of Postsynaptic Membrane Potential Regulation Of Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Stimulus Regulation Of Protein Phosphorylation Regulation Of Transcription From RNA Polymerase II Promoter Membrane Depolarization Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transferase Activity Startle Response Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Retinoic Acid Receptor Signaling Pathway Neuromuscular Process Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Protein Autophosphorylation Positive Regulation Of Phosphorylation Regulation Of RNA Metabolic Process Learning Positive Regulation Of Metabolic Process Response To Stress Gene Expression Synaptic Transmission Cardiac Muscle Tissue Growth Regulation Of Erythrocyte Differentiation Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Transcription, DNA-templated Regulation Of Synaptic Plasticity Palmitic Acid Biosynthetic Process Peptidyl-cysteine S-trans-nitrosylation Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process System Development Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Cellular Response To Steroid Hormone Stimulus Sensory Perception Of Mechanical Stimulus Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Phosphorylation	Regulation Of Cell Death Response To Gamma Radiation Positive Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Cellular Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Immune System Process Regulation Of Apoptotic Process Enzyme Linked Receptor Protein Signaling Pathway Response To Ionizing Radiation Response To Radiation Response To Inorganic Substance Response To Stimulus Regulation Of Cell Cycle Process Response To Organic Substance Protein Localization To Nucleus Viral Process Response To Abiotic Stimulus Cellular Response To Growth Factor Stimulus Response To Growth Factor Acute-phase Response Positive Regulation Of Cell Death Negative Regulation Of Reactive Oxygen Species Metabolic Process Immune Response Defense Response Regulation Of Muscle Cell Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Cellular Response To Peptide Hormone Stimulus Negative Regulation Of Catalytic Activity Regulation Of Cell Proliferation Cellular Response To Peptide Response To Metal Ion Negative Regulation Of Cellular Protein Metabolic Process Response To Stress Negative Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Translation In Response To Oxidative Stress DNA Ligation Involved In DNA Recombination Cellular Response To UV-C Inactivation Of MAPKK Activity Cellular Response To Vitamin B1 Inhibitory G-protein Coupled Receptor Phosphorylation Somatic Stem Cell Maintenance Cellular Response To Stress Proteolysis Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint
Tagcloud ?		1alpha apoptosis apoptotic bcl2 calmodulin enos ep300 epo explore expressions hhcy hif homocysteine hyperhomocysteinemia involvement itraq lower methoxyestradiol mtt neurons overexpression percentage presumed protects suppressed technique transfection tried	actinomycin biogenesis blunted blunting blunts caffeine chemotherapeutics combinatorial connected destabilize glioma indeed insults ly294 master mechanistic mimicked mtor nucleolar osteosarcoma pp242 rapamycin ribosome simultaneous stabilization temsirolimus triggered whereby wortmannin
Tagcloud (Difference) ?		1alpha apoptosis apoptotic bcl2 calmodulin enos ep300 epo explore expressions hhcy hif homocysteine hyperhomocysteinemia involvement itraq lower methoxyestradiol mtt neurons overexpression percentage presumed protects suppressed technique transfection tried	actinomycin biogenesis blunted blunting blunts caffeine chemotherapeutics combinatorial connected destabilize glioma indeed insults ly294 master mechanistic mimicked mtor nucleolar osteosarcoma pp242 rapamycin ribosome simultaneous stabilization temsirolimus triggered whereby wortmannin
Tagcloud (Intersection) ?