RPL11 and BLMH

Number of citations of the paper that reports this interaction (PMID 10353821)
1

Data Source:
HPRD (two hybrid, in vitro)

		RPL11	BLMH
Gene Name		ribosomal protein L11	bleomycin hydrolase
Image
Gene Ontology Annotations	Cellular Component	Nucleolus Cytosol Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding Poly(A) RNA Binding	Aminopeptidase Activity Carboxypeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation Translational Elongation Translational Termination Protein Targeting SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Protein Localization To Nucleus Ribosomal Large Subunit Biogenesis Cellular Protein Metabolic Process	Protein Polyubiquitination Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Proteolysis Response To Toxic Substance Response To Drug
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: ARFGAP1 BLMH C12orf5 CAMK2B HP IGF1R KRT40 KRTAP10-7 LIG4 MDM2 NEDD8 PAIP2 PML STAT3	14 interactors: AP1M2 APP CYP2C8 ECSIT KBTBD7 MAST1 NUDT12 PDPK1 RNF32 RPL11 RPL29 TRIO UBE2I WDYHV1
Entrez ID		6135	642
HPRD ID		10364	03870
Ensembl ID		ENSG00000142676	ENSG00000108578
Uniprot IDs		P62913 Q5VVD0	E7EMN3 Q13867
PDB IDs		3J3B	1CB5 2CB5
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Death Response To Gamma Radiation Positive Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Cellular Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Immune System Process Regulation Of Apoptotic Process Enzyme Linked Receptor Protein Signaling Pathway Response To Ionizing Radiation Response To Radiation Response To Inorganic Substance Response To Stimulus Regulation Of Cell Cycle Process Response To Organic Substance Protein Localization To Nucleus Viral Process Response To Abiotic Stimulus Cellular Response To Growth Factor Stimulus Response To Growth Factor Acute-phase Response Positive Regulation Of Cell Death Negative Regulation Of Reactive Oxygen Species Metabolic Process Immune Response Defense Response Regulation Of Muscle Cell Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Cellular Response To Peptide Hormone Stimulus Negative Regulation Of Catalytic Activity Regulation Of Cell Proliferation Cellular Response To Peptide Response To Metal Ion Negative Regulation Of Cellular Protein Metabolic Process Response To Stress Negative Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Translation In Response To Oxidative Stress DNA Ligation Involved In DNA Recombination Cellular Response To UV-C Inactivation Of MAPKK Activity Cellular Response To Vitamin B1 Inhibitory G-protein Coupled Receptor Phosphorylation Somatic Stem Cell Maintenance Cellular Response To Stress Proteolysis Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint	Viral Process NAD Catabolic Process Positive Regulation Of SUMO Transferase Activity Cellular Protein Metabolic Process Viral Transcription Axon Guidance Synaptic Growth At Neuromuscular Junction Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Protein Targeting Establishment Of Protein Localization To Endoplasmic Reticulum NADP Catabolic Process Collateral Sprouting In Absence Of Injury Aromatic Compound Catabolic Process Catabolic Process Regulation Of Receptor Activity Protein Localization To Endoplasmic Reticulum Axonogenesis Collateral Sprouting Axon Midline Choice Point Recognition Translational Termination MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process Establishment Of Localization In Cell Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Development Protein Metabolic Process MRNA Catabolic Process Protein Targeting To Membrane Cell Morphogenesis Involved In Neuron Differentiation Locomotion Axon Choice Point Recognition Chemotaxis Translational Elongation Cellular Protein Modification Process RNA Catabolic Process Protein Phosphorylation Neuron Projection Morphogenesis Cellular Protein Complex Disassembly Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Omega-hydroxylase P450 Pathway Viral Life Cycle Cellular Protein Localization Platelet Activation Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Neuron Remodeling Protein Complex Disassembly
Tagcloud ?		actinomycin biogenesis blunted blunting blunts caffeine chemotherapeutics combinatorial connected destabilize glioma indeed insults ly294 master mechanistic mimicked mtor nucleolar osteosarcoma pp242 rapamycin ribosome simultaneous stabilization temsirolimus triggered whereby wortmannin	17q11 accn1 addressing amiloride bleomycin breakpoint breakpoints centromeric contig correctly deletions disabilities dysmorphism extending gross hydrolase mb mosaicism neurofibromatosis nf1 premise retardation smallest sro supt6h tagged telomerically yac yacs
Tagcloud (Difference) ?		actinomycin biogenesis blunted blunting blunts caffeine chemotherapeutics combinatorial connected destabilize glioma indeed insults ly294 master mechanistic mimicked mtor nucleolar osteosarcoma pp242 rapamycin ribosome simultaneous stabilization temsirolimus triggered whereby wortmannin	17q11 accn1 addressing amiloride bleomycin breakpoint breakpoints centromeric contig correctly deletions disabilities dysmorphism extending gross hydrolase mb mosaicism neurofibromatosis nf1 premise retardation smallest sro supt6h tagged telomerically yac yacs
Tagcloud (Intersection) ?