CAMK2B and MORF4L1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CAMK2B	MORF4L1
Gene Name		calcium/calmodulin-dependent protein kinase II beta	mortality factor 4 like 1
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Microtubule Organizing Center Cytosol Plasma Membrane Endocytic Vesicle Membrane Sarcoplasmic Reticulum Membrane Spindle Midzone	Nucleoplasm Sin3 Complex NuA4 Histone Acetyltransferase Complex
	Molecular Function	Actin Binding Calmodulin-dependent Protein Kinase Activity Calmodulin Binding ATP Binding Protein Homodimerization Activity	Chromatin Binding Protein Binding Protein N-terminus Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Inhibitory G-protein Coupled Receptor Phosphorylation Protein Phosphorylation Calcium Ion Transport Signal Transduction Synaptic Transmission Positive Regulation Of Neuron Projection Development Regulation Of Skeletal Muscle Adaptation Peptidyl-serine Phosphorylation Cytokine-mediated Signaling Pathway Regulation Of Synaptic Transmission, Cholinergic Cellular Response To Heat Response To Cadmium Ion Protein Autophosphorylation Regulation Of Long-term Neuronal Synaptic Plasticity Neuromuscular Process Controlling Balance Regulation Of Synapse Structural Plasticity Regulation Of Calcium Ion Transport Interferon-gamma-mediated Signaling Pathway Activation Of Meiosis Involved In Egg Activation Regulation Of Dendritic Spine Development Positive Regulation Of Dendritic Spine Morphogenesis Positive Regulation Of Synapse Maturation Regulation Of Cellular Response To Heat Positive Regulation Of Apoptotic Signaling Pathway	Double-strand Break Repair Via Homologous Recombination Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Proliferation Histone Deacetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation
Pathways		Interferon Signaling Cytokine Signaling in Immune system Cellular response to heat stress CREB phosphorylation through the activation of Ras Trafficking of AMPA receptors Interferon gamma signaling HSF1-dependent transactivation Activation of NMDA receptor upon glutamate binding and postsynaptic events CREB phosphorylation through the activation of CaMKII Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Unblocking of NMDA receptor, glutamate binding and activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ras activation uopn Ca2+ infux through NMDA receptor Post NMDA receptor activation events Transmission across Chemical Synapses	Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Metabolic syndrome ( 22399527)	Coronary heart disease ( 21378988)
Protein-Protein Interactions		37 interactors: ACOT7 ACTN4 AP5B1 ATXN1 CAMK2D CAMK2N2 CCM2L COL4A3 ETS1 FAM171A2 GAPDH GRIN2A GRIN2B ITPKA KRTAP10-11 KRTAP19-5 KRTAP19-7 MAD2L2 MED18 MGAT5B MORF4L1 MRPL11 MVP PHKB PLCB3 POP5 RAP2B RBFOX2 RBPMS RPL11 RXRG SEMA4G SMYD3 SPRYD7 THRB TTC5 YWHAB	35 interactors: APP ARRDC3 BEND7 CALM1 CAMK2B CEP57L1 FAM9B FXR2 GMCL1 GOLGA2 HINFP HIST3H3 HMBOX1 IKZF1 L3MBTL3 LZTS2 MEOX1 MRFAP1 MRFAP1L1 MRGBP MSL1 NAB2 NAV2 PBXIP1 PHF12 RACGAP1 RB1 REL TFCP2 THAP1 TNIP1 TNNT1 TRIM41 ZBTB10 ZBTB9
Entrez ID		816	10933
HPRD ID		12127	09532
Ensembl ID		ENSG00000058404	ENSG00000185787
Uniprot IDs		A4D2J9 Q13554	B3KTM8 Q9UBU8
PDB IDs		3BHH	2AQL 2EFI 2F5J 2F5K 2LKM
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Excitatory Postsynaptic Membrane Potential Intracellular Receptor Signaling Pathway Cellular Response To Stimulus Regulation Of Postsynaptic Membrane Potential Regulation Of Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Stimulus Regulation Of Protein Phosphorylation Regulation Of Transcription From RNA Polymerase II Promoter Membrane Depolarization Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transferase Activity Startle Response Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Retinoic Acid Receptor Signaling Pathway Neuromuscular Process Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Protein Autophosphorylation Positive Regulation Of Phosphorylation Regulation Of RNA Metabolic Process Learning Positive Regulation Of Metabolic Process Response To Stress Gene Expression Synaptic Transmission Cardiac Muscle Tissue Growth Regulation Of Erythrocyte Differentiation Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Transcription, DNA-templated Regulation Of Synaptic Plasticity Palmitic Acid Biosynthetic Process Peptidyl-cysteine S-trans-nitrosylation Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process System Development Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Cellular Response To Steroid Hormone Stimulus Sensory Perception Of Mechanical Stimulus Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Phosphorylation	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Gene Expression RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Spindle Midzone Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cell Cycle Process Positive Regulation Of Transcription, DNA-templated Cell Cycle Immune System Process Multicellular Organismal Development Regulation Of Cell Division Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Process Biosynthetic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cell Division Neuron Maturation Cell Maturation Chromatin Modification Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Neutrophil Differentiation Cytokinesis, Initiation Of Separation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade
Tagcloud ?		1alpha apoptosis apoptotic bcl2 calmodulin enos ep300 epo explore expressions hhcy hif homocysteine hyperhomocysteinemia involvement itraq lower methoxyestradiol mtt neurons overexpression percentage presumed protects suppressed technique transfection tried	aligned backgrounds balance chromodomain controlling e3 elegans ensure fate finger germ glp homologue ligases likewise mrg mrg15 notch overproliferation proliferative proper proteasome rfp sensitized spatially stem suppresses threshold tightly
Tagcloud (Difference) ?		1alpha apoptosis apoptotic bcl2 calmodulin enos ep300 epo explore expressions hhcy hif homocysteine hyperhomocysteinemia involvement itraq lower methoxyestradiol mtt neurons overexpression percentage presumed protects suppressed technique transfection tried	aligned backgrounds balance chromodomain controlling e3 elegans ensure fate finger germ glp homologue ligases likewise mrg mrg15 notch overproliferation proliferative proper proteasome rfp sensitized spatially stem suppresses threshold tightly
Tagcloud (Intersection) ?