MYO9A and POLR2M

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MYO9A	POLR2M
Gene Name		myosin IXA	polymerase (RNA) II (DNA directed) polypeptide M
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Integral Component Of Membrane Unconventional Myosin Complex	Nuclear Envelope DNA-directed RNA Polymerase II, Holoenzyme Neuronal Cell Body
	Molecular Function	Motor Activity Actin Binding GTPase Activator Activity Protein Binding ATP Binding Metal Ion Binding	DNA-directed RNA Polymerase Activity
	Biological Process	Small GTPase Mediated Signal Transduction Visual Perception Metabolic Process Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	RNA Biosynthetic Process Maintenance Of ER Location
Pathways		Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS		Height ( 20881960) Metabolite levels (HVA/MHPG ratio) ( 23319000)
Protein-Protein Interactions		2 interactors: CDC42 POLR2M	19 interactors: AHSP ANKHD1 APOD CEBPG DGKZ HIGD1B KIAA1377 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410
Entrez ID		4649	81488
HPRD ID		05341	07575
Ensembl ID		ENSG00000066933	ENSG00000255529
Uniprot IDs		B2RTY4	P0CAP1 P0CAP2 Q6EEV4
PDB IDs			2KXS
Enriched GO Terms of Interacting Partners?		Maintenance Of ER Location Positive Regulation Of Hair Follicle Cell Proliferation Endoplasmic Reticulum Localization Actin Filament Branching Submandibular Salivary Gland Formation Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Organelle Localization Establishment Of Golgi Localization Positive Regulation Of Metalloenzyme Activity Neuron Fate Determination Epithelial-mesenchymal Cell Signaling Regulation Of Protein Heterodimerization Activity Keratinocyte Development Regulation Of Synapse Structural Plasticity Positive Regulation Of Pseudopodium Assembly Nuclear Migration Cardiac Conduction System Development Golgi Localization Filopodium Assembly Hair Follicle Placode Formation Macrophage Differentiation Regulation Of Attachment Of Spindle Microtubules To Kinetochore Dendritic Cell Migration Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Of Nucleus Localization Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Substrate Adhesion-dependent Cell Spreading Hair Follicle Morphogenesis Epithelial Cell-cell Adhesion Substantia Nigra Development Positive Regulation Of Cytokinesis Epidermis Morphogenesis Keratinization Salivary Gland Morphogenesis Nucleus Localization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Salivary Gland Development Regulation Of Filopodium Assembly Negative Regulation Of ERBB Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase Activity Cell Fate Determination Skin Morphogenesis Neural Nucleus Development Organelle Transport Along Microtubule Sprouting Angiogenesis Regulation Of Cytokinesis Regulation Of Lipid Kinase Activity Exocrine System Development	Viral Process Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of T Cell Migration Negative Regulation Of Lipoprotein Lipid Oxidation Transmission Of Virus Development Involved In Symbiotic Interaction Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Subthalamus Development Negative Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Lipoprotein Lipid Oxidation Mitotic DNA Damage Checkpoint Regulation Of Smooth Muscle Cell-matrix Adhesion Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Interaction With Host Regulation Of Mitotic Cell Cycle Negative Regulation Of Lymphocyte Migration Regulation Of Intracellular Transport Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Progesterone Receptor Signaling Pathway Developmental Process
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