GAN and MAP1B

Number of citations of the paper that reports this interaction (PMID 12147674)
18

Data Source:
HPRD (in vivo, in vitro)

		GAN	MAP1B
Gene Name		gigaxonin	microtubule-associated protein 1B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Cul3-RING Ubiquitin Ligase Complex	Cytoplasm Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Postsynaptic Density Cell Junction Dendritic Spine
	Molecular Function	Molecular_function Protein Binding	Structural Molecule Activity Protein Binding Microtubule Binding
	Biological Process	Protein Ubiquitination	Microtubule Bundle Formation Cellular Process Dendrite Development Negative Regulation Of Intracellular Transport Positive Regulation Of Axon Extension Mitochondrion Transport Along Microtubule Axon Extension Establishment Of Monopolar Cell Polarity
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057)
Protein-Protein Interactions		3 interactors: MAP1B TBCB UBA1	27 interactors: ACTB ANP32A ARHGEF11 DYNLL1 EEF1D FOS GABRR1 GABRR2 GAN GSK3B LRRK2 MAG MAGOH MAP1A MAPK8 MARCH5 MINK1 NXF1 NXF2 PAFAH1B1 RASSF1 SNCA SPP1 STAU1 STRAP U2AF1 U2AF2
Entrez ID		8139	4131
HPRD ID		05647	01139
Ensembl ID			ENSG00000131711
Uniprot IDs		B3KTC3 Q9H2C0	P46821 Q6PJD3 Q86X89
PDB IDs		2PPI 3HVE
Enriched GO Terms of Interacting Partners?		Establishment Of Monopolar Cell Polarity Mitochondrion Transport Along Microtubule Establishment Of Mitochondrion Localization	Nuclear Export MRNA Export From Nucleus RNA Localization Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus Regulation Of Mitochondrion Organization MRNA Transport RNA Transport Positive Regulation Of Mitochondrion Organization Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Cellular Component Organization Cellular Localization Negative Regulation Of Phosphorylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cytoplasmic Transport Negative Regulation Of Neuron Projection Development Substantia Nigra Development Regulation Of Cell Morphogenesis Termination Of RNA Polymerase II Transcription Signaling Cell Communication Cellular Response To Inorganic Substance Negative Regulation Of Cell Projection Organization Regulation Of Neuron Maturation Response To Metal Ion Regulation Of Axonogenesis Negative Regulation Of Cell Development Neural Nucleus Development Negative Regulation Of Protein Binding Synaptic Transmission Positive Regulation Of Programmed Cell Death Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Cell Death Regulation Of Neuron Projection Development Negative Regulation Of Neuron Differentiation Neuron Projection Morphogenesis Immune System Process Cellular Response To Oxidative Stress DNA-templated Transcription, Termination Neurotrophin TRK Receptor Signaling Pathway Regulation Of Mitochondrial Fission MRNA 3'-end Processing Nervous System Development Neurotrophin Signaling Pathway Regulation Of Intracellular Transport MAPK Cascade
Tagcloud ?		abolished acetylcholine adp aggregation aggregatory antagonist atropine attenuated b2 bradykinin diabetic gosha hoe improve jinki kg microg microm muscarinic name nitric o oxide platelet platelets rats simultaneous streptozotocin synthase	accelerated actin assembly barbed bundles cerevisiae coil coiled coisolated coronin coronins crn1delta crn1p cytoskeleton cytoskeletons dimerization filament filaments homologue linking links microtubule microtubules networks nucleation polymerization requirement saccharomyces stabilize
Tagcloud (Difference) ?		abolished acetylcholine adp aggregation aggregatory antagonist atropine attenuated b2 bradykinin diabetic gosha hoe improve jinki kg microg microm muscarinic name nitric o oxide platelet platelets rats simultaneous streptozotocin synthase	accelerated actin assembly barbed bundles cerevisiae coil coiled coisolated coronin coronins crn1delta crn1p cytoskeleton cytoskeletons dimerization filament filaments homologue linking links microtubule microtubules networks nucleation polymerization requirement saccharomyces stabilize
Tagcloud (Intersection) ?