GAN and TBCB

Number of citations of the paper that reports this interaction (PubMedID 16303566)
0

Data Source:
HPRD (in vivo, two hybrid)

		GAN	TBCB
Description		gigaxonin	tubulin folding cofactor B
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Cul3-RING Ubiquitin Ligase Complex	Nucleus Cytoplasm Cytosol Cytoskeleton Microtubule Cell Cortex Microtubule Cytoskeleton Microtubule Plus-end
	Molecular Function	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Protein Binding Alpha-tubulin Binding Microtubule Plus-end Binding
	Biological Process	Cytoskeleton Organization Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Tubulin Complex Assembly Post-chaperonin Tubulin Folding Pathway Nervous System Development Cell Differentiation Cytoplasmic Microtubule Organization
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Post-chaperonin tubulin folding pathway
Drugs
Diseases
GWAS		Age-related cataracts ( 25352737) Health literacy ( 31250787) Post bronchodilator FEV1 ( 26634245) Skin and soft tissue infections ( 33662382) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		4 interacting genes: ATG16L1 MAP1B TBCB UBA1	4 interacting genes: GAN PIWIL2 TUBA4A USP7
Entrez ID		8139	1155
HPRD ID		05647	03196
Ensembl ID		ENSG00000261609	ENSG00000105254
Uniprot IDs		A0A0S2Z4W2 B3KTC3 Q9H2C0	Q99426
PDB IDs		2PPI 3HVE
Enriched GO Terms of Interacting Partners?		Induction Of Synaptic Plasticity By Chemical Substance Vacuole-isolation Membrane Contact Site Post-chaperonin Tubulin Folding Pathway Tubulin Complex Assembly Microtubule-based Process Cytosol Autophagy Plasmacytoid Dendritic Cell Activation Plasmacytoid Dendritic Cell Differentiation Follicular B Cell Differentiation Germinal Center B Cell Differentiation Positive Regulation Of Synaptic Plasticity Varicosity Cell Projection Morphogenesis Response To Insecticide Peripheral Nervous System Axon Regeneration Microtubule-based Transport Odontoblast Differentiation Transport Along Microtubule Neuron Projection Morphogenesis Hippocampal Mossy Fiber Cytoskeleton-dependent Intracellular Transport Basal Dendrite Endosome Membrane Rough Endoplasmic Reticulum Membrane Ubiquitin-like Modifier Activating Enzyme Activity Ubiquitin Activating Enzyme Activity C-terminal Protein Lipidation Viral RNA Genome Replication Xenophagy Negative Regulation Of Dendrite Extension Negative Stranded Viral RNA Replication Atg12-Atg5-Atg16 Complex Regulation Of Developmental Growth Dendrite Arborization Microtubule Response To Vitamin A Response To Stress Apical Dendrite Somatodendritic Compartment Microtubule-based Movement Lysosomal Membrane Protein Localization To Phagophore Assembly Site Regulation Of Cell Growth Axon Corpus Callosum Development Endolysosome Membrane Ubiquitin-like Protein Transferase Activity Neuron Projection Arborization Viral Genome Replication	Regulation Of Establishment Of Protein Localization To Chromosome Negative Regulation Of Gene Expression, Epigenetic Rhythmic Process Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Circadian Rhythm Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Retrograde Transport, Endosome To Golgi Epigenetic Regulation Of Gene Expression Perinucleolar Chromocenter Transposable Element Silencing By PiRNA-mediated Heterochromatin Formation Transposable Element Silencing By MRNA Destabilization Secondary PiRNA Processing PiRNA Binding Regulation Of Meiosis I Germ-line Stem Cell Population Maintenance PiRNA-mediated Gene Silencing By MRNA Destabilization PET Complex Dense Body Positive Regulation Of Meiosis I Pi-body Monoubiquitinated Protein Deubiquitination Hydrolase Activity DNA Alkylation Repair Transcription-coupled Nucleotide-excision Repair Transposable Element Silencing By PiRNA-mediated DNA Methylation Chromatoid Body Negative Regulation Of Circadian Rhythm Regulation Of Telomere Capping Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Positive Regulation Of Meiotic Nuclear Division K48-linked Deubiquitinase Activity PiRNA Processing Positive Regulation Of Cytoplasmic Translation Negative Regulation Of Gluconeogenesis P Granule Regulatory NcRNA-mediated Heterochromatin Formation Transposable Element Silencing By Heterochromatin Formation Positive Regulation Of Meiotic Cell Cycle Deubiquitinase Activity Positive Regulation Of Catabolic Process Protein Ubiquitination Regulation Of Meiotic Nuclear Division Chromatin Remodeling RNA Endonuclease Activity Regulation Of Cytoplasmic Translation DNA Methylation-dependent Constitutive Heterochromatin Formation Protein Modification By Small Protein Conjugation Transposable Element Silencing
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