GRIP2 and GRIA3

Number of citations of the paper that reports this interaction (PMID 9768844)
61

Data Source:
HPRD (two hybrid)

		GRIP2	GRIA3
Gene Name		glutamate receptor interacting protein 2	glutamate receptor, ionotropic, AMPA 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane	Plasma Membrane Cell Junction Dendrite Endocytic Vesicle Membrane Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Selective Glutamate Receptor Complex Postsynaptic Membrane
	Molecular Function	Receptor Signaling Complex Scaffold Activity	Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Extracellular-glutamate-gated Ion Channel Activity
	Biological Process	Synaptic Transmission	Transport Glutamate Receptor Signaling Pathway Synaptic Transmission Ion Transmembrane Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic
Pathways		Trafficking of GluR2-containing AMPA receptors Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Trafficking of AMPA receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses	Trafficking of GluR2-containing AMPA receptors Activation of NMDA receptor upon glutamate binding and postsynaptic events Activation of AMPA receptors Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Trafficking of AMPA receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Unblocking of NMDA receptor, glutamate binding and activation Transmission across Chemical Synapses
Drugs			L-Glutamic Acid Lithium Aniracetam
Diseases
GWAS		Cognitive performance ( 19734545)
Protein-Protein Interactions		4 interactors: CSPG4 GFI1B GRIA2 GRIA3	11 interactors: ADRB2 GRIA2 GRIP1 GRIP2 GZMB LYN NSF PICK1 PPM1G SDCBP SQSTM1
Entrez ID		80852	2892
HPRD ID		18994	02378
Ensembl ID			ENSG00000125675
Uniprot IDs		Q9C0E4	P42263 Q17R51 Q5XKG2
PDB IDs		1V62 1X5R
Enriched GO Terms of Interacting Partners?		Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Glutamate Receptor Signaling Pathway Neuron-neuron Synaptic Transmission Dermatan Sulfate Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Metabolic Process Chondroitin Sulfate Catabolic Process	Cell-cell Signaling Synaptic Transmission Signaling Cell Communication Regulation Of Vesicle-mediated Transport Intracellular Transport Positive Regulation Of Cellular Metabolic Process Regulation Of Exocytosis Response To Extracellular Stimulus Protein Localization Cellular Response To Extracellular Stimulus Establishment Of Localization In Cell Regulation Of Signaling Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Metabolic Process Cellular Localization Positive Regulation Of Phosphorylation Apoptotic Signaling Pathway Signal Transduction Positive Regulation Of Oligodendrocyte Progenitor Proliferation Negative Regulation Of Mast Cell Proliferation Enzyme Linked Receptor Protein Signaling Pathway Protein Localization To Membrane Neuron Development Response To External Stimulus Response To Nutrient Levels Regulation Of Cellular Localization Intracellular Signal Transduction Ephrin Receptor Signaling Pathway Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Golgi Vesicle Docking Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Glial Cell Development Neuron Differentiation Cell Projection Organization Tolerance Induction To Self Antigen Fc Receptor Mediated Inhibitory Signaling Pathway Positive Regulation Of Dendritic Cell Apoptotic Process Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Extracellular Vesicular Exosome Assembly Cellular Response To Starvation Positive Regulation Of Signal Transduction Cell Differentiation Regulation Of Phosphorylation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Immune Response-inhibiting Cell Surface Receptor Signaling Pathway Granzyme-mediated Apoptotic Signaling Pathway
Tagcloud ?		akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668	agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gad2 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Difference) ?		akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668	agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gad2 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Intersection) ?