GRIP2

Description		glutamate receptor interacting protein 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane Glutamatergic Synapse
	Molecular Function
	Biological Process	Notch Signaling Pathway Artery Smooth Muscle Contraction Positive Regulation Of Blood Pressure Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse
Pathways		Trafficking of GluR2-containing AMPA receptors
Drugs
Diseases
GWAS		Cognitive performance ( 19734545) Sjögren's syndrome ( 28076899)
Interacting Genes		6 interacting genes: CSPG4 FMR1 FXR1 GFI1B GRIA2 GRIA3
Entrez ID		80852
HPRD ID		18994
Ensembl ID		ENSG00000144596
Uniprot IDs		Q9C0E4
PDB IDs		1V62 1X5R
Enriched GO Terms of Interacting Partners?		Dendritic Spine Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Glutamate Receptor Signaling Pathway RNA Strand Annealing Activity AMPA Glutamate Receptor Activity Intracellular Membraneless Organelle Positive Regulation Of Long-term Neuronal Synaptic Plasticity Glutamate-gated Receptor Activity Positive Regulation Of MiRNA-mediated Gene Silencing Modulation Of Chemical Synaptic Transmission Translation Regulator Activity Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Synaptic Plasticity Regulation Of MiRNA-mediated Gene Silencing AMPA Glutamate Receptor Complex Regulation Of Post-transcriptional Gene Silencing Postsynapse Postsynaptic Membrane Ionotropic Glutamate Receptor Signaling Pathway Ligand-gated Monoatomic Ion Channel Activity Presynaptic Modulation Of Chemical Synaptic Transmission Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential Ligand-gated Ion Channel Signaling Pathway Synaptic Transmission, Glutamatergic Synapse Molecular Condensate Scaffold Activity Regulation Of Neuronal Synaptic Plasticity Endocytic Vesicle Membrane Regulation Of Membrane Potential Cytoplasmic Ribonucleoprotein Granule Positive Regulation Of Intracellular Transport Of Viral Material Dendrite Amyloid-beta Binding Cytoplasmic Stress Granule Regulation Of Postsynaptic Membrane Potential Postsynaptic Density Membrane Dendritic Filopodium Histone H3 Reader Activity MRNA Transport MRNA 3'-UTR Binding Negative Regulation Of Long-term Synaptic Depression Growth Cone Filopodium Positive Regulation Of Synaptic Transmission Ligand-gated Monoatomic Cation Channel Activity RNA Transport Positive Regulation Of Translation Monoatomic Ion Channel Activity Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Cell Communication
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