CSNK1G2

Gene Name		casein kinase 1, gamma 2
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Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Membrane
	Molecular Function	Magnesium Ion Binding Glycoprotein Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Peptide Binding Phosphoprotein Binding
	Biological Process	Protein Phosphorylation Sphingolipid Metabolic Process Endocytosis Signal Transduction Regulation Of Cell Shape Wnt Signaling Pathway Peptidyl-serine Phosphorylation Sphingolipid Biosynthetic Process Small Molecule Metabolic Process Protein Autophosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		disassembly of the destruction complex and recruitment of AXIN to the membrane Sphingolipid metabolism Metabolism of lipids and lipoproteins misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT Sphingolipid de novo biosynthesis RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN Signaling by Wnt Signaling by WNT in cancer
Drugs
Diseases
GWAS
Protein-protein Interactions		13 interactors: APP APPBP2 C2orf44 COL4A3BP DBNDD2 KRTAP10-7 MTA1 NCK1 PER1 PPP1R14A RAP1GAP RUNDC3B SMAD3
Entrez ID		1455
HPRD ID		03738
Ensembl ID		ENSG00000133275
Uniprot IDs		P78368
PDB IDs		2C47
Enriched GO Terms of Interacting Partners?		Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Negative Regulation Of Phosphorylation Posttranscriptional Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Translation Regulation Of Inflammatory Response Regulation Of Catalytic Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Protein Phosphorylation Negative Regulation Of Cellular Protein Metabolic Process Response To Light Stimulus Positive Regulation Of Transforming Growth Factor Beta3 Production Positive Regulation Of Cap-dependent Translational Initiation Positive Regulation Of Cap-independent Translational Initiation Negative Regulation Of Microvillus Assembly Negative Regulation Of Protein Metabolic Process Circadian Regulation Of Gene Expression Response To External Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Circadian Rhythm Positive Regulation Of Translation In Response To Stress Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Synaptic Growth At Neuromuscular Junction ER To Golgi Ceramide Transport Positive Regulation Of Cytoplasmic Translation Positive Regulation Of Protein Autoubiquitination Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Response To Radiation Regulation Of Protein Phosphorylation Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Peptidyl-serine Dephosphorylation Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Regulation Of Protein Autoubiquitination Collateral Sprouting In Absence Of Injury Evasion Or Tolerance Of Host Defenses By Virus Positive Regulation Of Protein Metabolic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Ceramide Transport Positive Regulation Of Peptidase Activity Positive Regulation Of Metabolic Process
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