CSNK1G2 and COL4A3BP

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		CSNK1G2	COL4A3BP
Gene Name		casein kinase 1, gamma 2	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
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Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Membrane	Nucleoplasm Mitochondrion Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Magnesium Ion Binding Glycoprotein Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Peptide Binding Phosphoprotein Binding	Protein Kinase Activity Protein Binding Ceramide Transporter Activity Phosphatidylinositol-4-phosphate Binding Ceramide Binding
	Biological Process	Protein Phosphorylation Sphingolipid Metabolic Process Endocytosis Signal Transduction Regulation Of Cell Shape Wnt Signaling Pathway Peptidyl-serine Phosphorylation Sphingolipid Biosynthetic Process Small Molecule Metabolic Process Protein Autophosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway	Cell Morphogenesis In Utero Embryonic Development Heart Morphogenesis Protein Phosphorylation Sphingolipid Metabolic Process Ceramide Metabolic Process Muscle Contraction Immune Response Endoplasmic Reticulum Organization Signal Transduction Cell Proliferation Sphingolipid Biosynthetic Process Response To Endoplasmic Reticulum Stress ER To Golgi Ceramide Transport Small Molecule Metabolic Process Lipid Homeostasis Mitochondrion Morphogenesis
Pathways		disassembly of the destruction complex and recruitment of AXIN to the membrane Sphingolipid metabolism Metabolism of lipids and lipoproteins misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT Sphingolipid de novo biosynthesis RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN Signaling by Wnt Signaling by WNT in cancer
Drugs
Diseases
GWAS			Quantitative traits ( 19197348)
Protein-Protein Interactions		13 interactors: APP APPBP2 C2orf44 COL4A3BP DBNDD2 KRTAP10-7 MTA1 NCK1 PER1 PPP1R14A RAP1GAP RUNDC3B SMAD3	10 interactors: ACTL8 ARL6IP1 CBS COL4A3 CSNK1G2 ITGB3BP POM121 RTN3 RTN4 TGM2
Entrez ID		1455	10087
HPRD ID		03738	05246
Ensembl ID		ENSG00000133275	ENSG00000113163
Uniprot IDs		P78368	Q9Y5P4
PDB IDs		2C47	2E3M 2E3N 2E3O 2E3P 2E3Q 2E3R 2E3S 2RSG 2Z9Y 2Z9Z 3H3Q 3H3R 3H3S 3H3T
Enriched GO Terms of Interacting Partners?		Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Negative Regulation Of Phosphorylation Posttranscriptional Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Translation Regulation Of Inflammatory Response Regulation Of Catalytic Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Protein Phosphorylation Negative Regulation Of Cellular Protein Metabolic Process Response To Light Stimulus Positive Regulation Of Transforming Growth Factor Beta3 Production Positive Regulation Of Cap-dependent Translational Initiation Positive Regulation Of Cap-independent Translational Initiation Negative Regulation Of Microvillus Assembly Negative Regulation Of Protein Metabolic Process Circadian Regulation Of Gene Expression Response To External Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Circadian Rhythm Positive Regulation Of Translation In Response To Stress Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Synaptic Growth At Neuromuscular Junction ER To Golgi Ceramide Transport Positive Regulation Of Cytoplasmic Translation Positive Regulation Of Protein Autoubiquitination Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Response To Radiation Regulation Of Protein Phosphorylation Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Peptidyl-serine Dephosphorylation Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Regulation Of Protein Autoubiquitination Collateral Sprouting In Absence Of Injury Evasion Or Tolerance Of Host Defenses By Virus Positive Regulation Of Protein Metabolic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Ceramide Transport Positive Regulation Of Peptidase Activity Positive Regulation Of Metabolic Process	Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Organization Cysteine Biosynthetic Process From Serine Homocysteine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Apoptotic Process Programmed Cell Death Cell Death Death Endomembrane System Organization Cell Surface Receptor Signaling Pathway Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Transsulfuration Endothelial Cell Apoptotic Process Regulation Of Branching Morphogenesis Of A Nerve Cysteine Biosynthetic Process L-cysteine Catabolic Process Hydrogen Sulfide Biosynthetic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death L-serine Catabolic Process Positive Regulation Of Cell Death Hydrogen Sulfide Metabolic Process Regulation Of Apoptotic Process Salivary Gland Cavitation Regulation Of Cell Death Cysteine Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Neurotrophin Signaling Pathway Homocysteine Metabolic Process
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