NAA50 and BHLHE40

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NAA50	BHLHE40
Gene Name		N(alpha)-acetyltransferase 50, NatE catalytic subunit	basic helix-loop-helix family, member e40
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm NatA Complex Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Golgi Apparatus
	Molecular Function	Peptide Alpha-N-acetyltransferase Activity Protein Binding H4 Histone Acetyltransferase Activity Peptidyl-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Activating Transcription Factor Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Protein Homodimerization Activity BHLH Transcription Factor Binding MRF Binding Protein Heterodimerization Activity E-box Binding
	Biological Process	N-terminal Protein Amino Acid Acetylation Histone H4 Acetylation Mitotic Sister Chromatid Cohesion, Centromeric	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Circadian Rhythm Circadian Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated
Pathways			BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		4 interactors: BHLHE40 JMJD6 NAA10 NAA15	49 interactors: AAMP AANAT AES APH1A ARNTL BHLHE41 BRD7 BTRC CALML3 CCNK CDPF1 CHD3 COX5B DAB1 EHHADH ENO1 FBLN1 FBXW11 GMCL1P1 HDAC1 HIVEP1 KRTAP23-1 LARP4 MAGED1 MYOD1 NAA50 NOC4L NUMBL PDE6G PLEKHB2 PRKAA1 RBFOX1 RBM23 RBPMS RHOBTB3 RHOJ SETDB1 SIN3A SMYD1 SOX15 STAT3 STK19 TOB2 TOLLIP TTC23 TXNL4B VAC14 VIM ZHX1
Entrez ID		80218	8553
HPRD ID		14350	16050
Ensembl ID		ENSG00000121579	ENSG00000134107
Uniprot IDs		E7EQ69 Q9GZZ1	O14503 Q6IB83
PDB IDs		2OB0 2PSW 3TFY
Enriched GO Terms of Interacting Partners?		N-terminal Protein Amino Acid Acetylation N-terminal Protein Amino Acid Modification Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Protein Acetylation N-terminal Peptidyl-glutamic Acid Acetylation N-terminal Peptidyl-serine Acetylation Angiogenesis Recognition Of Apoptotic Cell Blood Vessel Morphogenesis Blood Vessel Development Phagocytosis, Recognition Vasculature Development Transcription, DNA-templated Entrainment Of Circadian Clock By Photoperiod RNA Biosynthetic Process Photoperiodism Entrainment Of Circadian Clock Protein Hydroxylation Macrophage Activation Apoptotic Cell Clearance Histone Demethylation Protein Demethylation Erythrocyte Development Cardiovascular System Development RNA Metabolic Process Cellular Protein Modification Process Peptidyl-amino Acid Modification Sprouting Angiogenesis Chromosome Organization Demethylation Anatomical Structure Formation Involved In Morphogenesis Gene Expression Regulation Of MRNA Splicing, Via Spliceosome T Cell Differentiation In Thymus Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Circadian Regulation Of Gene Expression	Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression Rhythmic Process RNA Metabolic Process Regulation Of Circadian Rhythm Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process RNA Biosynthetic Process Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of Gene Expression Circadian Rhythm Negative Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Circadian Rhythm Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Biosynthetic Process Histone Modification Chromatin Modification Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Circadian Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Cellular Process Macromolecule Biosynthetic Process Regulation Of Cellular Process Positive Regulation Of Skeletal Muscle Tissue Regeneration Positive Regulation Of Protein Metabolic Process Developmental Process Chromosome Organization Regulation Of Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Transcription, DNA-templated Protein Acetylation Biosynthetic Process
Tagcloud ?			ang angiogenic angiogenin cd31 colocalized fk fks glomeruli helix hypoxia lactate ldha microvascular mrnas mvd mvds nephrogenesis nks paired perinecrotic recapitulates reflected tubules univariable vegfa weaker wilms wts
Tagcloud (Difference) ?			ang angiogenic angiogenin cd31 colocalized fk fks glomeruli helix hypoxia lactate ldha microvascular mrnas mvd mvds nephrogenesis nks paired perinecrotic recapitulates reflected tubules univariable vegfa weaker wilms wts
Tagcloud (Intersection) ?