PRR36 and NPSR1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		PRR36	NPSR1
Description		proline rich 36	neuropeptide S receptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Plasma Membrane Membrane
	Molecular Function		G Protein-coupled Receptor Activity Vasopressin Receptor Activity Neuropeptide Receptor Activity
	Biological Process		Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Eating Behavior Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Righting Reflex Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Eating Behavior Negative Regulation Of Defecation
Pathways			Peptide ligand-binding receptors G alpha (q) signalling events G alpha (s) signalling events
Drugs			Halothane
Diseases
GWAS		Low density lipoprotein cholesterol levels ( 33339817) Total cholesterol levels ( 33339817)	Anti-chlamydia trachomatis IgG seropositivity ( 29967566) Asthma ( 29273806) Leisure-time exercise behaviour ( 30102679) Plasma anti-thyroglobulin levels ( 29678681) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		2 interacting genes: NPSR1 PELI2	16 interacting genes: ATP5F1A CCT2 ENTPD6 GABARAPL2 HLA-C IPO13 PGM2L1 PMPCB PRR36 RABGGTB SLC3A2 SLC41A3 SLC75A1 TERF2IP TMED10 TMEM101
Entrez ID		80164	387129
HPRD ID		18916	10547
Ensembl ID		ENSG00000183248	ENSG00000187258
Uniprot IDs		Q9H6K5	A0A090N8Z1 Q6W5P4
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Defecation Regulation Of Toll Signaling Pathway Positive Regulation Of MAPK Cascade Righting Reflex Negative Regulation Of Feeding Behavior Regulation Of Eating Behavior Negative Regulation Of Eating Behavior Vasopressin Receptor Activity Regulation Of MAPK Cascade Ubiquitin-ubiquitin Ligase Activity Reflex Neuropeptide Receptor Activity Regulation Of Feeding Behavior Eating Behavior Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Calcium Ion Transmembrane Transport Positive Regulation Of Signal Transduction Regulation Of Behavior Feeding Behavior Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Cell Communication Positive Regulation Of Signaling Neuropeptide Signaling Pathway Positive Regulation Of Calcium Ion Transport Regulation Of Intracellular Signal Transduction Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Monoatomic Ion Transmembrane Transport	Mitochondrial Processing Peptidase Complex Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Protein Processing Adenyl Ribonucleotide Binding Transmembrane Transport Guanosine-5'-triphosphate,3'-diphosphate Diphosphatase Activity Apical Pole Of Neuron Tetracycline Transmembrane Transport Tetracycline Transmembrane Transporter Activity Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Glucose-1,6-bisphosphate Synthase Activity
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