THOC7 and THOC5

Number of citations of the paper that reports this interaction (PMID 19059247)
5

Data Source:
HPRD (in vitro)

		THOC7	THOC5
Gene Name		THO complex 7 homolog (Drosophila)	THO complex 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nucleus Nucleoplasm Cytoplasm Nuclear Speck	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	RNA Binding Protein Binding	MRNA Binding Protein Binding
	Biological Process	MRNA Processing MRNA Export From Nucleus RNA Splicing Viral MRNA Export From Host Cell Nucleus	Cell Morphogenesis Blastocyst Development MRNA Processing MRNA Export From Nucleus RNA Splicing Regulation Of MRNA Export From Nucleus Stem Cell Division Monocyte Differentiation Positive Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Macrophage Differentiation Viral MRNA Export From Host Cell Nucleus Primitive Hemopoiesis Negative Regulation Of DNA Damage Checkpoint Regulation Of Stem Cell Division
Pathways
Drugs
Diseases
GWAS			Carotid atherosclerosis in HIV infection ( 20009918)
Protein-Protein Interactions		10 interactors: ALYREF CHD3 CKAP4 DDX39B GOT2 MED18 MED22 MED8 NIF3L1 THOC5	11 interactors: CSF1R CSNK2A1 DDX39B LIG4 LSM3 NXF1 PPIL1 PRKCA THOC1 THOC7 ZNF830
Entrez ID		80145	8563
HPRD ID		17632	16650
Ensembl ID		ENSG00000163634	ENSG00000100296
Uniprot IDs		Q6I9Y2	Q13769
PDB IDs
Enriched GO Terms of Interacting Partners?		Viral MRNA Export From Host Cell Nucleus Intracellular Transport Of Virus Positive Regulation Of DNA-templated Transcription, Elongation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of DNA Damage Checkpoint Regulation Of DNA-templated Transcription, Elongation Cellular Nitrogen Compound Metabolic Process MRNA Export From Nucleus Nitrogen Compound Metabolic Process RNA Export From Nucleus Regulation Of DNA Damage Checkpoint Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nuclear Export MRNA Transport Regulation Of RNA Metabolic Process RNA Transport RNA Localization RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Viral Life Cycle Regulation Of Cell Cycle Checkpoint Nucleocytoplasmic Transport Nuclear Transport Transcription From RNA Polymerase II Promoter RNA Splicing Nucleobase-containing Compound Metabolic Process Biosynthetic Process MRNA Processing Cellular Metabolic Process Regulation Of Metabolic Process Transcription, DNA-templated Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process MRNA Metabolic Process RNA Biosynthetic Process Viral Process Positive Regulation Of Transcription, DNA-templated Regulation Of Response To DNA Damage Stimulus RNA Processing Fumarate Metabolic Process Dihydrobiopterin Metabolic Process RNA Secondary Structure Unwinding Regulation Of Stem Cell Division	Viral MRNA Export From Host Cell Nucleus MRNA Export From Nucleus RNA Export From Nucleus MRNA Transport Nuclear Export Intracellular Transport Of Virus RNA Splicing RNA Transport RNA Localization MRNA Processing Negative Regulation Of DNA Damage Checkpoint MRNA Metabolic Process Viral Process RNA Processing Nucleocytoplasmic Transport Nuclear Transport Regulation Of DNA Damage Checkpoint Gene Expression Regulation Of Cell Cycle Negative Regulation Of Cell Cycle Positive Regulation Of DNA-templated Transcription, Elongation Viral Life Cycle Regulation Of Cell Cycle Checkpoint MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cytoplasmic Transport DNA Replication Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of DNA-templated Transcription, Elongation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cell Proliferation DNA Ligation Involved In DNA Recombination Positive Regulation Of Dense Core Granule Biogenesis Negative Regulation Of Isotype Switching To IgA Isotypes Nitrogen Compound Metabolic Process Apoptotic Process Regulation Of Mitotic Cell Cycle Programmed Cell Death Histone H3-T6 Phosphorylation Macrophage Colony-stimulating Factor Signaling Pathway Cell Death Death DNA-dependent DNA Replication Regulation Of Cell Cycle Process Cellular Metabolic Process Intestinal Epithelial Structure Maintenance RNA Secondary Structure Unwinding
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