THOC7 and GOT2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		THOC7	GOT2
Gene Name		THO complex 7 homolog (Drosophila)	glutamic-oxaloacetic transaminase 2, mitochondrial
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nucleus Nucleoplasm Cytoplasm Nuclear Speck	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Protein Binding	L-aspartate:2-oxoglutarate Aminotransferase Activity Kynurenine-oxoglutarate Transaminase Activity Pyridoxal Phosphate Binding Poly(A) RNA Binding L-phenylalanine:2-oxoglutarate Aminotransferase Activity
	Biological Process	MRNA Processing MRNA Export From Nucleus RNA Splicing Viral MRNA Export From Host Cell Nucleus	Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis 2-oxoglutarate Metabolic Process Oxaloacetate Metabolic Process Aspartate Metabolic Process Aspartate Biosynthetic Process Aspartate Catabolic Process Glutamate Metabolic Process Cellular Amino Acid Biosynthetic Process Pathogenesis Fatty Acid Transport 4-hydroxyproline Catabolic Process Glutamate Catabolic Process To Aspartate Glutamate Catabolic Process To 2-oxoglutarate Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Response To Ethanol L-kynurenine Metabolic Process
Pathways			Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Amino acid synthesis and interconversion (transamination) Metabolism of carbohydrates Metabolism of amino acids and derivatives
Drugs			Pyridoxal Phosphate L-Aspartic Acid L-Glutamic Acid 4\'-Deoxy-4\'-Acetylyamino-Pyridoxal-5\'-Phosphate
Diseases
GWAS			Aortic root size ( 21223598) QT interval ( 19305408)
Protein-Protein Interactions		10 interactors: ALYREF CHD3 CKAP4 DDX39B GOT2 MED18 MED22 MED8 NIF3L1 THOC5	10 interactors: APCS CCL21 GAPDH GLRX GLUD1 HSPA8 MDH2 PC THOC7 ZDHHC6
Entrez ID		80145	2806
HPRD ID		17632	00684
Ensembl ID		ENSG00000163634	ENSG00000125166
Uniprot IDs		Q6I9Y2	E7ERW2 P00505
PDB IDs
Enriched GO Terms of Interacting Partners?		Viral MRNA Export From Host Cell Nucleus Intracellular Transport Of Virus Positive Regulation Of DNA-templated Transcription, Elongation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of DNA Damage Checkpoint Regulation Of DNA-templated Transcription, Elongation Cellular Nitrogen Compound Metabolic Process MRNA Export From Nucleus Nitrogen Compound Metabolic Process RNA Export From Nucleus Regulation Of DNA Damage Checkpoint Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nuclear Export MRNA Transport Regulation Of RNA Metabolic Process RNA Transport RNA Localization RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Viral Life Cycle Regulation Of Cell Cycle Checkpoint Nucleocytoplasmic Transport Nuclear Transport Transcription From RNA Polymerase II Promoter RNA Splicing Nucleobase-containing Compound Metabolic Process Biosynthetic Process MRNA Processing Cellular Metabolic Process Regulation Of Metabolic Process Transcription, DNA-templated Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process MRNA Metabolic Process RNA Biosynthetic Process Viral Process Positive Regulation Of Transcription, DNA-templated Regulation Of Response To DNA Damage Stimulus RNA Processing Fumarate Metabolic Process Dihydrobiopterin Metabolic Process RNA Secondary Structure Unwinding Regulation Of Stem Cell Division	Gluconeogenesis Hexose Biosynthetic Process Dicarboxylic Acid Metabolic Process Oxaloacetate Metabolic Process Glucose Metabolic Process Carbohydrate Biosynthetic Process Pathogenesis Hexose Metabolic Process Monosaccharide Metabolic Process Tricarboxylic Acid Metabolic Process Protein Deglutathionylation Positive Regulation Of Myeloid Dendritic Cell Chemotaxis Negative Regulation Of Dendritic Cell Dendrite Assembly Dendritic Cell Dendrite Assembly Negative Regulation Of Fibril Organization Peptidyl-cysteine S-trans-nitrosylation Carboxylic Acid Metabolic Process Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Mesangial Cell-matrix Adhesion Negative Regulation Of Exo-alpha-sialidase Activity Organic Acid Metabolic Process Pyruvate Metabolic Process Regulation Of Dendritic Cell Dendrite Assembly Regulation Of Fibril Organization Small Molecule Metabolic Process Negative Regulation Of Leukocyte Tethering Or Rolling Clathrin Coat Disassembly Peptidyl-cysteine S-nitrosylation Establishment Of T Cell Polarity Oxidation-reduction Process Negative Regulation Of Monocyte Differentiation Glutamate Catabolic Process Positive Regulation Of Dendritic Cell Chemotaxis Cellular Metabolic Process Positive Regulation Of Transport Viral MRNA Export From Host Cell Nucleus Glutamate Biosynthetic Process Cellular Protein Metabolic Process Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Negative Regulation Of Locomotion Biotin Metabolic Process Positive Regulation Of Pseudopodium Assembly Negative Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Dicarboxylic Acid Catabolic Process Chaperone-mediated Protein Complex Assembly Protein Folding Regulation Of Monocyte Differentiation Dendritic Cell Chemotaxis
Tagcloud ?			aggravating anxa1 banks bedside confidently cons fth1 ftl gliosis immunochemical infarct infarcted infarcts itraq lagging leak malate mdh2 mortem plex pros proteome proteomics putamen shuttle slc25a11 slc25a12 tca vim
Tagcloud (Difference) ?			aggravating anxa1 banks bedside confidently cons fth1 ftl gliosis immunochemical infarct infarcted infarcts itraq lagging leak malate mdh2 mortem plex pros proteome proteomics putamen shuttle slc25a11 slc25a12 tca vim
Tagcloud (Intersection) ?