THOC7 and CKAP4

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		THOC7	CKAP4
Gene Name		THO complex 7 homolog (Drosophila)	cytoskeleton-associated protein 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nucleus Nucleoplasm Cytoplasm Nuclear Speck	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Particle Cytoskeleton Plasma Membrane Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Protein Binding	Poly(A) RNA Binding
	Biological Process	MRNA Processing MRNA Export From Nucleus RNA Splicing Viral MRNA Export From Host Cell Nucleus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: ALYREF CHD3 CKAP4 DDX39B GOT2 MED18 MED22 MED8 NIF3L1 THOC5	11 interactors: ASCC2 ATF4 CCDC53 HAMP MLH1 MVP NDUFB7 NKX3-1 PLAT THOC7 TSNAX
Entrez ID		80145	10970
HPRD ID		17632	16717
Ensembl ID		ENSG00000163634	ENSG00000136026
Uniprot IDs		Q6I9Y2	Q07065
PDB IDs
Enriched GO Terms of Interacting Partners?		Viral MRNA Export From Host Cell Nucleus Intracellular Transport Of Virus Positive Regulation Of DNA-templated Transcription, Elongation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of DNA Damage Checkpoint Regulation Of DNA-templated Transcription, Elongation Cellular Nitrogen Compound Metabolic Process MRNA Export From Nucleus Nitrogen Compound Metabolic Process RNA Export From Nucleus Regulation Of DNA Damage Checkpoint Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nuclear Export MRNA Transport Regulation Of RNA Metabolic Process RNA Transport RNA Localization RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Viral Life Cycle Regulation Of Cell Cycle Checkpoint Nucleocytoplasmic Transport Nuclear Transport Transcription From RNA Polymerase II Promoter RNA Splicing Nucleobase-containing Compound Metabolic Process Biosynthetic Process MRNA Processing Cellular Metabolic Process Regulation Of Metabolic Process Transcription, DNA-templated Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process MRNA Metabolic Process RNA Biosynthetic Process Viral Process Positive Regulation Of Transcription, DNA-templated Regulation Of Response To DNA Damage Stimulus RNA Processing Fumarate Metabolic Process Dihydrobiopterin Metabolic Process RNA Secondary Structure Unwinding Regulation Of Stem Cell Division	Meiotic Spindle Midzone Assembly Meiotic Metaphase I Plate Congression Negative Regulation Of Mitotic Recombination Positive Regulation Of Androgen Secretion Zymogen Activation MRNA Transport Positive Regulation Of Ovulation Negative Regulation Of Estrogen Receptor Binding RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation RNA Transport Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Localization Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Cellular Nitrogen Compound Metabolic Process Cellular Response To Steroid Hormone Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Intrinsic Apoptotic Signaling Pathway Viral MRNA Export From Host Cell Nucleus Plasminogen Activation Negative Regulation Of Receptor Binding
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