TMEM62 and LTA4H

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TMEM62	LTA4H
Gene Name		transmembrane protein 62	leukotriene A4 hydrolase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Nucleoplasm Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function		Aminopeptidase Activity Epoxide Hydrolase Activity Leukotriene-A4 Hydrolase Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Poly(A) RNA Binding
	Biological Process		Proteolysis Leukotriene Metabolic Process Inflammatory Response Arachidonic Acid Metabolic Process Leukotriene Biosynthetic Process Peptide Catabolic Process Small Molecule Metabolic Process
Pathways			Arachidonic acid metabolism Metabolism of lipids and lipoproteins Synthesis of Leukotrienes (LT) and Eoxins (EX)
Drugs			N-[3-[(1-Aminoethyl)(Hydroxy)Phosphoryl]-2-(1,1\'-Biphenyl-4-Ylmethyl)Propanoyl]Alanine 3-(Benzyloxy)Pyridin-2-Amine Bestatin 5-[2-(1H-pyrrol-1-yl)ethoxy]-1H-indole N-(pyridin-3-ylmethyl)aniline (4-fluorophenyl)(pyridin-4-yl)methanone 1-(2,2\'-bithiophen-5-yl)methanamine N-[4-(benzyloxy)phenyl]glycinamide (2S)-2-amino-5-oxo-5-[(4-phenylmethoxyphenyl)amino]pentanoic acid 4-amino-N-[4-(benzyloxy)phenyl]butanamide N-methyl-1-(2-thiophen-2-ylphenyl)methanamine {4-[(2R)-pyrrolidin-2-ylmethoxy]phenyl}(4-thiophen-3-ylphenyl)methanone (R)-pyridin-4-yl[4-(2-pyrrolidin-1-ylethoxy)phenyl]methanol 1-(4-thiophen-2-ylphenyl)methanamine N-benzyl-4-[(2R)-pyrrolidin-2-ylmethoxy]aniline 4-(2-amino-1,3-thiazol-4-yl)phenol N-[(2R)-2-benzyl-4-(hydroxyamino)-4-oxobutanoyl]-L-alanine 5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol
Diseases
GWAS			Height ( 20966902)
Protein-Protein Interactions		7 interactors: APEH CSE1L HSPA5 LTA4H PTPN6 SLC27A6 ZNF287	3 interactors: ARPC3 TINF2 TMEM62
Entrez ID		80021	4048
HPRD ID		08669	01056
Ensembl ID		ENSG00000137842	ENSG00000111144
Uniprot IDs		Q0P6H9	P09960
PDB IDs			1GW6 1H19 1HS6 1SQM 2R59 2VJ8 3B7R 3B7S 3B7T 3B7U 3CHO 3CHP 3CHQ 3CHR 3CHS 3FH5 3FH7 3FH8 3FHE 3FTS 3FTU 3FTV 3FTW 3FTX 3FTY 3FTZ 3FU0 3FU3 3FU5 3FU6 3FUD 3FUE 3FUF 3FUH 3FUI 3FUJ 3FUK 3FUL 3FUM 3FUN 3U9W 4DPR
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Folding In Endoplasmic Reticulum Long-chain Fatty Acid Metabolic Process Abortive Mitotic Cell Cycle Cerebellum Structural Organization	Negative Regulation Of Protein ADP-ribosylation Regulation Of Protein ADP-ribosylation Positive Regulation Of Organelle Organization Negative Regulation Of Protein Glycosylation Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome, Telomeric Region Telomere Assembly Negative Regulation Of Telomere Maintenance Regulation Of Protein Glycosylation Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Glycoprotein Metabolic Process Regulation Of Telomere Maintenance Regulation Of Organelle Organization Regulation Of Glycoprotein Biosynthetic Process Protein Localization To Chromosome Telomere Maintenance Via Telomere Lengthening Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of DNA Replication Actin Nucleation Telomere Maintenance Regulation Of Cellular Component Organization Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Ephrin Receptor Signaling Pathway Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization
Tagcloud ?			69kda abilities alb amylase capability de depletion desmoplakin elute eluted fluids iggs immunoaffinity immunoglobulins page plastin remove removing saa salivary sequentially spots tag triple twofold unmasked venue visualization visualized
Tagcloud (Difference) ?			69kda abilities alb amylase capability de depletion desmoplakin elute eluted fluids iggs immunoaffinity immunoglobulins page plastin remove removing saa salivary sequentially spots tag triple twofold unmasked venue visualization visualized
Tagcloud (Intersection) ?