TMEM62 and CSE1L

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		TMEM62	CSE1L
Name		transmembrane protein 62	chromosome segregation 1 like
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Cytosol Membrane Extracellular Exosome
	Molecular Function	Protein Binding Hydrolase Activity	Nuclear Export Signal Receptor Activity Protein Binding Small GTPase Binding
	Biological Process	None	Protein Import Into Nucleus Protein Export From Nucleus Intracellular Protein Transport Protein Transport
GWAS		No GWAS studies recorded	Anger ( 24489884 ) Extremely high intelligence ( 29520040 ) General cognitive ability ( 29844566 ) Intelligence ( 28530673 ) Intelligence (MTAG) ( 29326435 ) Loneliness ( 29970889 ) Loneliness (MTAG) ( 29970889 ) Non-response to citalopram or escitalopram and depression ( 27622933 ) Response to fluticasone propionate/salmeterol in chronic obstructive pulmonary disease ( 31299468 ) Subjective well-being ( 27089181 )
Interacting Genes		8 interacting genes: APEH CSE1L F2RL1 HSPA5 LTA4H PTPN6 SLC27A6 ZNF287	20 interacting genes: BIRC2 CDC42 CDH1 DUX4 HNRNPL KPNA1 KPNA4 KPNA6 KPNB1 MAPK6 MTNR1B PPP5C RAN RNF10 RPL22 STAT1 SUMO2 TMEM62 YWHAG YWHAQ
Entrez ID		80021	1434
HPRD ID		08669	03217
Ensembl ID		ENSG00000137842	ENSG00000124207
Uniprot IDs		Q0P6H9	A0A384NKW7 P55060
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Neutrophil Activation Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Renin Secretion Into Blood Stream Regulation Of Protein Folding In Endoplasmic Reticulum Leukotriene-A4 Hydrolase Activity Tripeptide Aminopeptidase Activity Tertiary Granule Lumen Epididymis Development Ficolin-1-rich Granule Lumen Extracellular Exosome Omega Peptidase Activity Proteinase-activated Receptor Activity Positive Regulation Of Glomerular Filtration Regulation Of Renin Secretion Into Blood Stream Positive Regulation Of Eosinophil Degranulation Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Cerebellum Structural Organization Cell Activation Involved In Immune Response Mature Conventional Dendritic Cell Differentiation Regulation Of Interleukin-6 Production Leukocyte Activation Involved In Immune Response Leukocyte Proliferation Myeloid Leukocyte Activation Positive Regulation Of Killing Of Cells Of Another Organism Thrombin-activated Receptor Activity Regulation Of ATF6-mediated Unfolded Protein Response CD27 Signaling Pathway Negative Regulation Of Mast Cell Activation Involved In Immune Response	NLS-dependent Protein Nuclear Import Complex Nuclear Import Signal Receptor Activity Nuclear Localization Sequence Binding NLS-bearing Protein Import Into Nucleus Protein Import Into Nucleus Import Into Nucleus Protein-containing Complex Protein Localization To Nucleus Nuclear Pore Nuclear Transport Nucleocytoplasmic Transport RNA Import Into Nucleus Postsynapse To Nucleus Signaling Pathway Glutamatergic Synapse Establishment Of Protein Localization To Organelle Importin-alpha Family Protein Binding Cytoplasm Protein Localization To Organelle Intracellular Protein Localization Nucleus Protein Domain Specific Binding Response To Hydrogen Peroxide Positive Regulation Of Hippo Signaling Intracellular Protein Transport Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Establishment Of Protein Localization Ubiquitin-like Protein Ligase Binding Cytosol Identical Protein Binding Positive Regulation Of Cell Communication Positive Regulation Of RNA Metabolic Process Response To Reactive Oxygen Species Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Intracellular Signal Transduction Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Localization Substantia Nigra Development Focal Adhesion Positive Regulation Of Protein Import Into Nucleus RNA Binding Regulation Of Hippo Signaling Hsp90 Protein Binding Translation At Presynapse Negative Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Extracellular Exosome