FRMD1 and RAB2A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FRMD1	RAB2A
Description		FERM domain containing 1	RAB2A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasmic Side Of Apical Plasma Membrane	Golgi Membrane Autophagosome Membrane Acrosomal Vesicle Nucleus Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Extracellular Exosome
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Hippo Signaling	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Protein Transport Vesicle-mediated Transport Macroautophagy Autophagosome-lysosome Fusion
Pathways			Golgi Cisternae Pericentriolar Stack Reorganization RAB geranylgeranylation
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IL-2) ( 22610502) Metabolite levels ( 23823483) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Aspartate aminotransferase levels ( 33547301) Autoimmune thyroid disease ( 32581359) Estimated glomerular filtration rate ( 31152163) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 32888494) Systemic sclerosis ( 31672989) Total cholesterol levels ( 29083408)
Interacting Genes		2 interacting genes: PIN4 RAB2A	29 interacting genes: BLZF1 CBFB CCDC125 CEBPA CFL2 FAM114A1 FAM114A2 FRMD1 GAA GAPDH GARIN4 GARIN6 GDI2 GOLGA2 GORASP2 HES6 ICA1 MAPK6 MAPKAPK3 OTOS PMAIP1 PRKCI RBSN RGS2 SGSM2 STAMBPL1 TBC1D25 TMEM70 TRIM7
Entrez ID		79981	5862
HPRD ID		10997	01539
Ensembl ID		ENSG00000153303	ENSG00000104388
Uniprot IDs		A0A2R8Y4L9 A0A2R8Y6M2 A0A2R8Y7X7 Q8N878	P61019
PDB IDs			1Z0A
Enriched GO Terms of Interacting Partners?		Preribosome Bent DNA Binding Autophagosome-lysosome Fusion
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