UBA5 and APEH

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UBA5	APEH
Gene Name		ubiquitin-like modifier activating enzyme 5	acylaminoacyl-peptide hydrolase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Intracellular Membrane-bounded Organelle	Cytoplasm Nuclear Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding ATP Binding Metal Ion Binding UFM1 Activating Enzyme Activity	Serine-type Endopeptidase Activity Omega Peptidase Activity Poly(A) RNA Binding
	Biological Process	Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Protein Ufmylation Protein Polyufmylation	Proteolysis Beta-amyloid Metabolic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Ulcerative colitis ( 21297633)
Protein-Protein Interactions		3 interactors: APEH GABARAPL2 UFM1	5 interactors: IST1 LGALS8 SHBG TMEM62 UBA5
Entrez ID		79876	327
HPRD ID		15598	00034
Ensembl ID		ENSG00000081307	ENSG00000164062
Uniprot IDs		Q9GZZ9	P13798
PDB IDs		3GUC 3H8V
Enriched GO Terms of Interacting Partners?		Protein Polyufmylation Protein Ufmylation Cellular Response To Nitrogen Starvation Nucleophagy Beta-amyloid Metabolic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Mitochondrion Degradation Positive Regulation Of ATPase Activity Organelle Disassembly Regulation Of ATPase Activity Autophagic Vacuole Assembly Intra-Golgi Vesicle-mediated Transport Macroautophagy Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway	Primary Spermatocyte Growth Viral Capsid Secondary Envelopment Plasma Cell Differentiation Viral Release From Host Cell Protein Polyufmylation Abscission Protein Ufmylation Positive Regulation Of Collateral Sprouting Mature B Cell Differentiation Involved In Immune Response Mature B Cell Differentiation Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Tagcloud ?		17beta abrogated activating asc1 bound coactivator displaced e1 e2 eralpha establish estradiol knockdown largely maintains nonufmylated polyufmylation prevented promoted promoters promoting protease screened src1 tamoxifen transactivation ufm1 ufmylation ufsp2	3p21 acylpeptide add assign backcross band chromosomally chromosome chromosomes conservation dnas fourth hydrolase interspecific longest mapped myl3 myosin osteosarcoma p22 parathyroid pthr rpthrec4 segregated spanning synteny tf transferrin umr
Tagcloud (Difference) ?		17beta abrogated activating asc1 bound coactivator displaced e1 e2 eralpha establish estradiol knockdown largely maintains nonufmylated polyufmylation prevented promoted promoters promoting protease screened src1 tamoxifen transactivation ufm1 ufmylation ufsp2	3p21 acylpeptide add assign backcross band chromosomally chromosome chromosomes conservation dnas fourth hydrolase interspecific longest mapped myl3 myosin osteosarcoma p22 parathyroid pthr rpthrec4 segregated spanning synteny tf transferrin umr
Tagcloud (Intersection) ?