APEH and UBA5

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		APEH	UBA5
Description		acylaminoacyl-peptide hydrolase	ubiquitin like modifier activating enzyme 5
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Nuclear Membrane Extracellular Exosome Ficolin-1-rich Granule Lumen	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane
	Molecular Function	RNA Binding Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Omega Peptidase Activity Hydrolase Activity Identical Protein Binding	Nucleotide Binding Protein Binding ATP Binding Zinc Ion Binding Ubiquitin-like Modifier Activating Enzyme Activity Protein Homodimerization Activity Metal Ion Binding UFM1 Activating Enzyme Activity
	Biological Process	Translational Termination Proteolysis Amyloid-beta Metabolic Process	Erythrocyte Differentiation Megakaryocyte Differentiation Regulation Of Type II Interferon Production Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Neuromuscular Process Reticulophagy Protein Ufmylation Protein K69-linked Ufmylation
Pathways		Neutrophil degranulation Eukaryotic Translation Termination	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Extremely high intelligence ( 29520040) Feeling tense ( 29500382) Feeling worry ( 29500382) Household income ( 31844048) Inflammatory bowel disease ( 28067908) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 21297633 28067908)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		7 interacting genes: CEBPA IST1 LGALS8 RUNX1 SHBG TMEM62 UBA5	8 interacting genes: APEH GABARAPL2 OGT PKD1P1 TMEM132D UBE2D2 UBE2K UBE2L3
Entrez ID		327	79876
HPRD ID		00034	15598
Ensembl ID		ENSG00000164062	ENSG00000081307
Uniprot IDs		P13798	Q9GZZ9
PDB IDs			3GUC 3H8V 5HKH 5IA8 5IAA 5L95 6H77 6H78 6H8C 7NVK 7NW1 7OVC
Enriched GO Terms of Interacting Partners?		Hematopoietic Stem Cell Proliferation Leukocyte Differentiation Stem Cell Proliferation Regulation Of Proteolysis Positive Regulation Of Cell Activation Myeloid Cell Differentiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding UFM1 Activating Enzyme Activity Core-binding Factor Complex Negative Regulation Of Hemopoiesis Regeneration CHOP-C/EBP Complex Response To Vitamin B2 C/EBP Complex Lymphatic Endothelial Cell Migration MIT Domain Binding Cardiac Muscle Tissue Regeneration Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Myeloid Leukocyte Differentiation Regulation Of Cell Activation White Fat Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Macroautophagy Androgen Binding Protein K69-linked Ufmylation Protein Homodimerization Activity DNA-binding Transcription Factor Binding Regulation Of Multicellular Organismal Process Positive Regulation Of Multicellular Organismal Process Plasma Cell Differentiation Positive Regulation Of Proteolysis Response To Phenylpropanoid Xenophagy Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Positive Regulation Of CD8-positive, Alpha-beta T Cell Activation Positive Regulation Of Granulocyte Differentiation Fat Cell Proliferation Regulation Of Cell Development Protein Domain Specific Binding Positive Regulation Of Cell Differentiation Negative Regulation Of Granulocyte Differentiation ESCRT III Complex Disassembly ESCRT Complex Disassembly Ubiquitin-like Modifier Activating Enzyme Activity Protein Ufmylation Transcription Cis-regulatory Region Binding Positive Regulation Of T Cell Activation Peripheral Nervous System Neuron Development Urea Cycle	Ubiquitin Conjugating Enzyme Activity Proteolysis Regulation Of Proteasomal Protein Catabolic Process Ubiquitin-protein Transferase Activity Protein Polyubiquitination Ubiquitin Protein Ligase Binding Mitophagy Regulation Of Protein Catabolic Process Regulation Of Proteolysis Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Proteasomal Protein Catabolic Process Autophagy Of Mitochondrion Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Catabolic Process Protein K48-linked Ubiquitination Omega Peptidase Activity Negative Regulation Of Protein Catabolic Process Protein O-acetylglucosaminyltransferase Activity Protein-containing Complex Disassembly Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Protein-containing Complex Organization Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Modification Process Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Free Ubiquitin Chain Polymerization Protein Ubiquitination Regulation Of Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Macroautophagy Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Protein Ubiquitination Protein Modification Process Ubiquitin-protein Transferase Activator Activity Regulation Of Transcription By Glucose Positive Regulation Of Peptidyl-threonine Phosphorylation Cellular Response To Nitrogen Starvation Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Transferase Activity NSL Complex Post-translational Protein Modification Regulation Of Post-translational Protein Modification
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?