APEH and UBA5

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		APEH	UBA5
Gene Name		acylaminoacyl-peptide hydrolase	ubiquitin-like modifier activating enzyme 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Nuclear Membrane Extracellular Vesicular Exosome	Nucleus Cytoplasm Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Serine-type Endopeptidase Activity Omega Peptidase Activity Poly(A) RNA Binding	Protein Binding ATP Binding Metal Ion Binding UFM1 Activating Enzyme Activity
	Biological Process	Proteolysis Beta-amyloid Metabolic Process	Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Protein Ufmylation Protein Polyufmylation
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		Ulcerative colitis ( 21297633)
Protein-Protein Interactions		5 interactors: IST1 LGALS8 SHBG TMEM62 UBA5	3 interactors: APEH GABARAPL2 UFM1
Entrez ID		327	79876
HPRD ID		00034	15598
Ensembl ID		ENSG00000164062	ENSG00000081307
Uniprot IDs		P13798	Q9GZZ9
PDB IDs			3GUC 3H8V
Enriched GO Terms of Interacting Partners?		Primary Spermatocyte Growth Viral Capsid Secondary Envelopment Plasma Cell Differentiation Viral Release From Host Cell Protein Polyufmylation Abscission Protein Ufmylation Positive Regulation Of Collateral Sprouting Mature B Cell Differentiation Involved In Immune Response Mature B Cell Differentiation Regulation Of Intracellular Estrogen Receptor Signaling Pathway	Protein Polyufmylation Protein Ufmylation Cellular Response To Nitrogen Starvation Nucleophagy Beta-amyloid Metabolic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Mitochondrion Degradation Positive Regulation Of ATPase Activity Organelle Disassembly Regulation Of ATPase Activity Autophagic Vacuole Assembly Intra-Golgi Vesicle-mediated Transport Macroautophagy Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Tagcloud ?		3p21 acylpeptide add assign backcross band chromosomally chromosome chromosomes conservation dnas fourth hydrolase interspecific longest mapped myl3 myosin osteosarcoma p22 parathyroid pthr rpthrec4 segregated spanning synteny tf transferrin umr	17beta abrogated activating asc1 bound coactivator displaced e1 e2 eralpha establish estradiol knockdown largely maintains nonufmylated polyufmylation prevented promoted promoters promoting protease screened src1 tamoxifen transactivation ufm1 ufmylation ufsp2
Tagcloud (Difference) ?		3p21 acylpeptide add assign backcross band chromosomally chromosome chromosomes conservation dnas fourth hydrolase interspecific longest mapped myl3 myosin osteosarcoma p22 parathyroid pthr rpthrec4 segregated spanning synteny tf transferrin umr	17beta abrogated activating asc1 bound coactivator displaced e1 e2 eralpha establish estradiol knockdown largely maintains nonufmylated polyufmylation prevented promoted promoters promoting protease screened src1 tamoxifen transactivation ufm1 ufmylation ufsp2
Tagcloud (Intersection) ?