UBA5

Gene Name		ubiquitin-like modifier activating enzyme 5
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding ATP Binding Metal Ion Binding UFM1 Activating Enzyme Activity
	Biological Process	Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Protein Ufmylation Protein Polyufmylation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: APEH GABARAPL2 UFM1
Entrez ID		79876
HPRD ID		15598
Ensembl ID		ENSG00000081307
Uniprot IDs		Q9GZZ9
PDB IDs		3GUC 3H8V
Enriched GO Terms of Interacting Partners?		Protein Polyufmylation Protein Ufmylation Cellular Response To Nitrogen Starvation Nucleophagy Beta-amyloid Metabolic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Mitochondrion Degradation Positive Regulation Of ATPase Activity Organelle Disassembly Regulation Of ATPase Activity Autophagic Vacuole Assembly Intra-Golgi Vesicle-mediated Transport Macroautophagy Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Tagcloud ?		17beta abrogated activating asc1 bound coactivator displaced e1 e2 eralpha establish estradiol knockdown largely maintains nonufmylated polyufmylation prevented promoted promoters promoting protease screened src1 tamoxifen transactivation ufm1 ufmylation ufsp2