APEH

Name	acylaminoacyl-peptide hydrolase
Structure	No pdb structure
Interactors	7 interactors: CEBPA IST1 LGALS8 RUNX1 SHBG TMEM62 UBA5
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Nuclear Membrane Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Binding Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Omega Peptidase Activity Hydrolase Activity Identical Protein Binding
	Biological Process	Translational Termination Proteolysis Amyloid-beta Metabolic Process
Pathways	Neutrophil degranulation Eukaryotic Translation Termination
GWAS	Body mass index ( 26426971 ) Brain morphology (min-P) ( 32665545 ) Brain morphology (MOSTest) ( 32665545 ) Cortical surface area (MOSTest) ( 32665545 ) Crohn's disease ( 28067908 ) Extremely high intelligence ( 29520040 ) Feeling tense ( 29500382 ) Feeling worry ( 29500382 ) Household income ( 31844048 ) Inflammatory bowel disease ( 28067908 ) Regular attendance at a gym or sports club ( 29970889 ) Regular attendance at a religious group ( 29970889 ) Sleep duration (short sleep) ( 30846698 ) Subcortical volume (min-P) ( 32665545 ) Subcortical volume (MOSTest) ( 32665545 ) Ulcerative colitis ( 21297633 28067908 )
Entrez ID	327
HPRD ID	00034
Ensembl ID	ENSG00000164062
Uniprot IDs	P13798
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Hematopoietic Stem Cell Proliferation Leukocyte Differentiation Stem Cell Proliferation Regulation Of Proteolysis Positive Regulation Of Cell Activation Myeloid Cell Differentiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding UFM1 Activating Enzyme Activity Core-binding Factor Complex Negative Regulation Of Hemopoiesis Regeneration CHOP-C/EBP Complex Response To Vitamin B2 C/EBP Complex Lymphatic Endothelial Cell Migration MIT Domain Binding Cardiac Muscle Tissue Regeneration Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Myeloid Leukocyte Differentiation Regulation Of Cell Activation White Fat Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Macroautophagy Androgen Binding Protein K69-linked Ufmylation Protein Homodimerization Activity DNA-binding Transcription Factor Binding Regulation Of Multicellular Organismal Process Positive Regulation Of Multicellular Organismal Process Plasma Cell Differentiation Positive Regulation Of Proteolysis Response To Phenylpropanoid Xenophagy Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Positive Regulation Of CD8-positive, Alpha-beta T Cell Activation Positive Regulation Of Granulocyte Differentiation Fat Cell Proliferation Regulation Of Cell Development Protein Domain Specific Binding Positive Regulation Of Cell Differentiation Negative Regulation Of Granulocyte Differentiation ESCRT III Complex Disassembly ESCRT Complex Disassembly Ubiquitin-like Modifier Activating Enzyme Activity Protein Ufmylation Transcription Cis-regulatory Region Binding Positive Regulation Of T Cell Activation Peripheral Nervous System Neuron Development Urea Cycle